| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 33 | 33 | 10 | 17 | 4.52 | .307 | 1.30 | 7.3 | 4.4 | 9.7 | 217.0 | 177 | 111 | 109 | 31 | 105 | 233 | 0 | 0 | 0 | 0 | 16 | 6 | 7 | 4.24 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 32 | 32 | 6 | 14 | 6.30 | .354 | 1.62 | 10.5 | 4.1 | 6.9 | 178.2 | 208 | 126 | 125 | 40 | 81 | 137 | 0 | 0 | 0 | 0 | 11 | 5 | 5 | 5.83 |
| SP | Perry, G.Perry, Gaylord # >> | 34 | 1972 | R | 68 | 32 | 32 | 12 | 15 | 4.54 | .308 | 1.32 | 8.9 | 3.0 | 5.8 | 247.2 | 244 | 129 | 125 | 32 | 82 | 158 | 11 | 0 | 0 | 1 | 15 | 5 | 7 | 4.46 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 59 | 30 | 30 | 11 | 13 | 4.86 | .308 | 1.29 | 7.9 | 3.8 | 7.3 | 205.2 | 180 | 113 | 111 | 40 | 86 | 166 | 5 | 0 | 0 | 1 | 16 | 8 | 7 | 5.29 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 85 | 0 | 6 | 2 | 2.90 | .296 | 1.21 | 6.4 | 4.5 | 8.7 | 99.1 | 70 | 32 | 32 | 7 | 50 | 96 | 0 | 10 | 2 | 0 | 0 | 5 | 0 | 3.65 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 65 | 0 | 8 | 3 | 3.46 | .296 | 1.22 | 6.2 | 4.8 | 10.2 | 75.1 | 52 | 30 | 29 | 6 | 40 | 85 | 0 | 10 | 2 | 0 | 0 | 3 | 7 | 3.49 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 49 | 0 | 1 | 2 | 4.14 | .293 | 1.23 | 6.7 | 4.5 | 9.9 | 58.2 | 43 | 28 | 27 | 12 | 29 | 64 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 5.03 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 56 | 36 | 0 | 1 | 4 | 1.98 | .250 | 1.00 | 5.3 | 3.7 | 10.5 | 41.0 | 24 | 10 | 9 | 3 | 17 | 48 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2.85 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 47 | 36 | 0 | 1 | 0 | 3.25 | .285 | 1.15 | 8.0 | 2.5 | 5.3 | 44.1 | 39 | 16 | 16 | 4 | 12 | 26 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 3.95 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 2 | 0 | 1 | 1 | 15.43 | .533 | 3.43 | 22.5 | 13.5 | 4.5 | 2.1 | 5 | 4 | 4 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 13.00 |
| SP | Dickey, R.Dickey, R.A. >> | 38 | 2012 | R | 42 | 12 | 0 | 1 | 3 | 9.00 | .400 | 1.96 | 11.3 | 6.4 | 7.5 | 24.0 | 30 | 24 | 24 | 4 | 17 | 20 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 5.75 |