| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 36 | 36 | 14 | 12 | 3.57 | .307 | 1.31 | 7.4 | 4.4 | 9.1 | 236.2 | 193 | 98 | 94 | 23 | 116 | 238 | 0 | 0 | 0 | 0 | 26 | 5 | 1 | 3.79 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 78 | 33 | 33 | 12 | 13 | 5.67 | .332 | 1.46 | 9.9 | 3.3 | 7.2 | 201.2 | 222 | 129 | 127 | 33 | 73 | 160 | 3 | 0 | 0 | 1 | 14 | 6 | 7 | 4.72 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 69 | 33 | 33 | 17 | 12 | 4.45 | .325 | 1.42 | 9.1 | 3.7 | 7.2 | 232.1 | 234 | 115 | 115 | 31 | 96 | 185 | 5 | 0 | 0 | 0 | 18 | 6 | 4 | 4.46 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 64 | 31 | 31 | 9 | 15 | 6.01 | .343 | 1.53 | 10.3 | 3.5 | 8.3 | 169.1 | 193 | 117 | 113 | 30 | 66 | 155 | 0 | 0 | 0 | 0 | 14 | 6 | 4 | 4.75 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 86 | 0 | 6 | 4 | 2.84 | .266 | 1.07 | 7.1 | 2.4 | 10.4 | 92.0 | 73 | 35 | 29 | 13 | 25 | 106 | 0 | 39 | 3 | 0 | 0 | 2 | 3 | 3.41 |
| SU | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 81 | 0 | 2 | 2 | 3.61 | .309 | 1.32 | 8.3 | 3.6 | 11.1 | 92.1 | 85 | 38 | 37 | 17 | 37 | 113 | 0 | 1 | 7 | 0 | 0 | 2 | 3 | 4.22 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 65 | 0 | 0 | 2 | 2.69 | .275 | 1.12 | 5.3 | 4.9 | 10.5 | 70.1 | 41 | 23 | 21 | 7 | 38 | 82 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 3.63 |
| SP | Strider, S.Strider, Spencer >> | 24 | 2023 | R | 39 | 27 | 0 | 3 | 7 | 6.27 | .366 | 1.71 | 13.0 | 2.5 | 13.0 | 47.1 | 68 | 33 | 33 | 7 | 13 | 68 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 2.94 |