| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 23 | 23 | 9 | 6 | 3.61 | .295 | 1.24 | 6.5 | 4.6 | 9.0 | 142.0 | 103 | 57 | 57 | 19 | 73 | 142 | 1 | 0 | 0 | 0 | 12 | 2 | 2 | 4.32 |
| SP | Richard, J.Richard, J.R. † $ >> | 30 | 1980 | R | 93 | 22 | 22 | 12 | 4 | 3.63 | .305 | 1.32 | 7.2 | 4.7 | 7.1 | 143.2 | 115 | 58 | 58 | 9 | 74 | 113 | 1 | 0 | 0 | 1 | 13 | 0 | 1 | 3.79 |
| SP | Johnson, R.Johnson, Randy † $ >> | 41 | 2004 | L | 90 | 23 | 23 | 12 | 4 | 4.26 | .296 | 1.26 | 9.0 | 2.4 | 9.7 | 160.2 | 160 | 76 | 76 | 30 | 42 | 172 | 4 | 0 | 0 | 0 | 12 | 1 | 1 | 4.09 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 83 | 22 | 22 | 12 | 7 | 4.18 | .283 | 1.16 | 8.5 | 2.1 | 6.6 | 165.2 | 155 | 77 | 77 | 23 | 38 | 121 | 9 | 0 | 0 | 0 | 10 | 3 | 5 | 4.09 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 76 | 22 | 22 | 12 | 7 | 3.26 | .291 | 1.20 | 7.7 | 3.2 | 6.5 | 160.0 | 136 | 66 | 58 | 18 | 56 | 116 | 5 | 0 | 0 | 1 | 13 | 5 | 5 | 4.16 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 33 | 0 | 2 | 3 | 2.67 | .289 | 1.16 | 6.5 | 4.1 | 10.9 | 33.2 | 24 | 10 | 10 | 1 | 15 | 40 | 0 | 23 | 1 | 0 | 0 | 2 | 2 | 2.52 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 56 | 0 | 3 | 2 | 3.97 | .306 | 1.32 | 5.8 | 6.3 | 11.4 | 56.2 | 36 | 27 | 25 | 6 | 39 | 71 | 0 | 1 | 2 | 0 | 0 | 0 | 5 | 3.95 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 23 | 0 | 2 | 2 | 3.48 | .295 | 1.26 | 8.1 | 3.6 | 12.2 | 20.2 | 18 | 8 | 8 | 2 | 8 | 27 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.80 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 16 | 0 | 2 | 1 | 1.50 | .239 | 0.94 | 5.0 | 3.5 | 9.0 | 18.0 | 10 | 6 | 3 | 1 | 7 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.89 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 17 | 0 | 0 | 1 | 2.89 | .243 | 0.96 | 7.0 | 2.0 | 10.0 | 18.2 | 14 | 8 | 6 | 3 | 4 | 20 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.61 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 69 | 8 | 0 | 2 | 0 | 5.40 | .242 | 0.96 | 4.5 | 4.5 | 4.5 | 8.1 | 4 | 5 | 5 | 2 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.75 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 70 | 10 | 2 | 1 | 3 | 5.20 | .310 | 1.32 | 8.8 | 3.3 | 7.0 | 36.1 | 35 | 22 | 21 | 6 | 13 | 28 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 4.78 |