| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 32 | 32 | 10 | 8 | 4.03 | .298 | 1.26 | 9.0 | 2.4 | 6.4 | 183.1 | 183 | 89 | 82 | 25 | 48 | 130 | 1 | 0 | 0 | 1 | 13 | 2 | 3 | 4.17 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 83 | 32 | 32 | 13 | 17 | 4.75 | .313 | 1.34 | 8.9 | 3.1 | 6.3 | 242.1 | 240 | 140 | 128 | 39 | 84 | 170 | 14 | 0 | 0 | 0 | 14 | 7 | 4 | 4.82 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 75 | 30 | 30 | 4 | 10 | 3.55 | .294 | 1.21 | 8.0 | 2.9 | 9.5 | 144.1 | 128 | 58 | 57 | 25 | 47 | 152 | 0 | 0 | 0 | 0 | 7 | 5 | 3 | 4.23 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 73 | 0 | 6 | 4 | 3.31 | .267 | 1.07 | 6.6 | 3.0 | 10.3 | 87.0 | 64 | 34 | 32 | 11 | 29 | 100 | 0 | 8 | 4 | 0 | 0 | 2 | 0 | 3.41 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 37 | 0 | 3 | 0 | 3.38 | .294 | 1.23 | 7.7 | 3.4 | 10.4 | 40.0 | 34 | 15 | 15 | 8 | 15 | 46 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.50 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 66 | 1 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 9.0 | 0.0 | 0.0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 64 | 18 | 0 | 1 | 8 | 4.97 | .320 | 1.41 | 9.3 | 3.4 | 9.0 | 29.0 | 30 | 17 | 16 | 6 | 11 | 29 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 4.83 |