| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 36 | 36 | 17 | 13 | 3.59 | .285 | 1.18 | 7.9 | 2.7 | 7.9 | 261.0 | 230 | 106 | 104 | 36 | 78 | 228 | 6 | 0 | 0 | 1 | 22 | 4 | 6 | 3.99 |
| SP | Maddux, G.Maddux, Greg † # >> | 29 | 1995 | R | 90 | 34 | 34 | 20 | 7 | 3.22 | .262 | 1.05 | 7.8 | 1.7 | 6.3 | 254.1 | 221 | 92 | 91 | 25 | 47 | 179 | 11 | 0 | 0 | 7 | 24 | 3 | 4 | 3.46 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 88 | 33 | 33 | 12 | 7 | 4.43 | .308 | 1.31 | 8.5 | 3.3 | 7.7 | 203.1 | 191 | 102 | 100 | 28 | 75 | 174 | 0 | 0 | 0 | 0 | 15 | 5 | 12 | 4.26 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 77 | 33 | 31 | 15 | 11 | 3.86 | .300 | 1.25 | 8.1 | 3.2 | 7.2 | 219.1 | 197 | 96 | 94 | 21 | 77 | 175 | 7 | 0 | 0 | 3 | 17 | 8 | 4 | 3.81 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 85 | 0 | 8 | 8 | 2.61 | .258 | 1.04 | 6.2 | 3.3 | 11.4 | 120.2 | 82 | 37 | 35 | 9 | 44 | 152 | 0 | 15 | 1 | 0 | 0 | 0 | 4 | 2.54 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 92 | 82 | 0 | 6 | 3 | 2.08 | .250 | 0.99 | 4.7 | 4.2 | 11.5 | 95.0 | 50 | 23 | 22 | 8 | 44 | 121 | 0 | 17 | 4 | 0 | 0 | 1 | 4 | 2.97 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 83 | 53 | 0 | 3 | 3 | 2.13 | .261 | 1.06 | 8.4 | 1.1 | 6.7 | 63.1 | 59 | 15 | 15 | 5 | 8 | 47 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 2.92 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 27 | 0 | 3 | 2 | 1.07 | .217 | 0.83 | 5.7 | 1.9 | 9.8 | 33.2 | 21 | 4 | 4 | 1 | 7 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.85 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 82 | 20 | 0 | 3 | 0 | 2.00 | .302 | 1.19 | 7.3 | 3.3 | 5.0 | 27.0 | 22 | 6 | 6 | 3 | 10 | 15 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 4.78 |