| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 21 | 21 | 3 | 8 | 4.59 | .325 | 1.45 | 9.0 | 4.1 | 8.4 | 119.2 | 119 | 63 | 61 | 12 | 54 | 111 | 0 | 0 | 0 | 0 | 13 | 0 | 7 | 3.81 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 21 | 21 | 8 | 10 | 4.13 | .305 | 1.29 | 9.3 | 2.3 | 6.5 | 146.0 | 151 | 74 | 67 | 22 | 37 | 105 | 9 | 0 | 0 | 1 | 10 | 4 | 1 | 4.36 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 19 | 19 | 7 | 8 | 4.77 | .308 | 1.30 | 9.7 | 2.1 | 4.9 | 122.2 | 131 | 67 | 65 | 17 | 29 | 66 | 6 | 0 | 0 | 1 | 7 | 4 | 1 | 4.54 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 17 | 17 | 3 | 11 | 7.07 | .359 | 1.66 | 11.3 | 3.7 | 5.3 | 90.1 | 113 | 74 | 71 | 19 | 37 | 53 | 3 | 0 | 0 | 0 | 4 | 2 | 1 | 5.87 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 49 | 0 | 4 | 0 | 2.28 | .272 | 1.07 | 6.2 | 3.5 | 9.0 | 67.0 | 46 | 18 | 17 | 5 | 26 | 67 | 0 | 3 | 2 | 0 | 0 | 3 | 4 | 3.27 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 46 | 0 | 3 | 4 | 5.72 | .351 | 1.61 | 7.4 | 7.2 | 8.8 | 56.2 | 46 | 37 | 36 | 8 | 45 | 55 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 5.36 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 34 | 0 | 1 | 3 | 5.23 | .345 | 1.53 | 9.6 | 4.2 | 8.0 | 43.0 | 46 | 28 | 25 | 10 | 20 | 38 | 0 | 3 | 1 | 0 | 0 | 2 | 4 | 5.79 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 56 | 7 | 1 | 2 | 1 | 4.29 | .323 | 1.43 | 8.1 | 4.7 | 3.9 | 21.0 | 19 | 10 | 10 | 5 | 11 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 6.81 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 48 | 29 | 0 | 1 | 3 | 5.13 | .371 | 1.73 | 13.0 | 2.7 | 5.0 | 54.1 | 78 | 38 | 31 | 7 | 16 | 30 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 4.57 |