| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 21 | 21 | 10 | 8 | 2.93 | .294 | 1.24 | 7.6 | 3.7 | 9.4 | 150.1 | 126 | 59 | 49 | 16 | 61 | 156 | 2 | 0 | 0 | 1 | 15 | 1 | 4 | 3.55 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 19 | 19 | 9 | 4 | 3.92 | .308 | 1.31 | 9.5 | 2.3 | 4.3 | 108.0 | 114 | 52 | 47 | 9 | 27 | 51 | 0 | 0 | 0 | 0 | 7 | 3 | 1 | 3.97 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 19 | 19 | 9 | 7 | 4.31 | .312 | 1.34 | 8.9 | 3.2 | 5.9 | 148.1 | 147 | 85 | 71 | 16 | 52 | 97 | 5 | 0 | 0 | 1 | 10 | 3 | 0 | 4.21 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 19 | 19 | 8 | 6 | 4.73 | .324 | 1.42 | 9.3 | 3.5 | 4.7 | 133.1 | 138 | 72 | 70 | 17 | 51 | 70 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.83 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 52 | 0 | 5 | 6 | 2.81 | .264 | 1.06 | 7.5 | 2.1 | 8.2 | 77.0 | 64 | 28 | 24 | 9 | 18 | 70 | 0 | 5 | 4 | 0 | 0 | 1 | 2 | 3.44 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 48 | 0 | 2 | 1 | 3.16 | .266 | 1.05 | 6.0 | 3.5 | 7.6 | 57.0 | 38 | 20 | 20 | 2 | 22 | 48 | 0 | 12 | 4 | 0 | 0 | 2 | 0 | 3.04 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 24 | 0 | 2 | 1 | 1.95 | .346 | 1.55 | 6.3 | 8.0 | 10.0 | 27.2 | 19 | 6 | 6 | 0 | 24 | 30 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.56 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 25 | 0 | 2 | 1 | 2.93 | .281 | 1.11 | 7.2 | 3.0 | 10.5 | 30.2 | 24 | 10 | 10 | 3 | 10 | 35 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 3.17 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 4 | 0 | 1 | 0 | 0.00 | .231 | 0.90 | 3.0 | 6.0 | 15.0 | 3.1 | 1 | 0 | 0 | 0 | 2 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.67 |