| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 11 | 12 | 3.49 | .249 | 0.99 | 6.7 | 2.2 | 9.2 | 209.0 | 156 | 84 | 81 | 24 | 50 | 213 | 2 | 0 | 0 | 0 | 24 | 2 | 0 | 3.20 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 32 | 32 | 5 | 20 | 4.99 | .331 | 1.47 | 9.8 | 3.5 | 6.8 | 200.1 | 217 | 122 | 111 | 23 | 78 | 152 | 1 | 0 | 0 | 0 | 14 | 2 | 13 | 4.18 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 33 | 32 | 11 | 12 | 5.01 | .326 | 1.43 | 9.2 | 3.7 | 5.2 | 188.2 | 192 | 108 | 105 | 27 | 78 | 108 | 2 | 0 | 0 | 0 | 15 | 4 | 7 | 5.03 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 33 | 31 | 13 | 14 | 4.01 | .302 | 1.25 | 7.9 | 3.3 | 5.4 | 200.0 | 176 | 95 | 89 | 16 | 73 | 121 | 9 | 0 | 0 | 1 | 18 | 10 | 2 | 4.08 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 76 | 0 | 3 | 3 | 4.65 | .308 | 1.33 | 9.2 | 2.7 | 7.9 | 89.0 | 91 | 49 | 46 | 16 | 27 | 78 | 0 | 2 | 5 | 0 | 0 | 1 | 1 | 4.53 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 90 | 0 | 2 | 3 | 2.46 | .281 | 1.14 | 6.3 | 4.0 | 8.3 | 91.1 | 64 | 27 | 25 | 4 | 40 | 84 | 0 | 3 | 3 | 0 | 0 | 3 | 4 | 3.14 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 63 | 0 | 4 | 3 | 5.08 | .345 | 1.57 | 10.2 | 4.0 | 3.9 | 88.2 | 100 | 56 | 50 | 16 | 39 | 38 | 0 | 1 | 0 | 0 | 0 | 1 | 8 | 5.86 |