| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 8 | 8 | 4 | 3 | 4.53 | .326 | 1.41 | 8.6 | 4.2 | 5.3 | 49.2 | 47 | 26 | 25 | 4 | 23 | 29 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 4.41 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 8 | 8 | 4 | 3 | 4.96 | .317 | 1.32 | 9.6 | 2.4 | 9.8 | 45.1 | 48 | 26 | 25 | 5 | 12 | 49 | 1 | 0 | 0 | 1 | 4 | 3 | 0 | 3.27 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 8 | 8 | 1 | 4 | 5.86 | .327 | 1.44 | 11.2 | 2.0 | 4.1 | 50.2 | 62 | 33 | 33 | 8 | 11 | 23 | 1 | 0 | 0 | 0 | 2 | 1 | 1 | 4.88 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 16 | 0 | 2 | 1 | 2.25 | .231 | 0.90 | 4.5 | 3.6 | 7.7 | 20.0 | 10 | 5 | 5 | 2 | 8 | 17 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 3.80 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 14 | 0 | 1 | 0 | 3.21 | .250 | 1.00 | 5.8 | 3.2 | 7.1 | 14.0 | 9 | 5 | 5 | 1 | 5 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 15 | 0 | 2 | 0 | 3.38 | .325 | 1.39 | 9.0 | 4.0 | 8.5 | 18.2 | 18 | 7 | 7 | 0 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.61 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 12 | 0 | 0 | 0 | 5.82 | .271 | 1.06 | 8.5 | 1.1 | 5.3 | 17.0 | 16 | 11 | 11 | 2 | 2 | 10 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.88 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 11 | 0 | 1 | 0 | 3.07 | .353 | 1.64 | 12.9 | 2.6 | 5.8 | 14.2 | 20 | 5 | 5 | 3 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.36 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 10 | 0 | 0 | 0 | 9.28 | .396 | 1.97 | 11.7 | 7.2 | 9.0 | 10.2 | 13 | 11 | 11 | 3 | 8 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.30 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 3 | 0 | 0 | 0 | 4.50 | .379 | 1.83 | 10.5 | 6.0 | 10.5 | 6.0 | 7 | 4 | 3 | 0 | 4 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.67 |