| SP | deGrom, J.deGrom, Jacob † >> | 30 | 2018 | R | 96 | 27 | 27 | 13 | 10 | 3.20 | .260 | 1.05 | 7.1 | 2.3 | 8.9 | 208.0 | 164 | 77 | 74 | 23 | 54 | 206 | 10 | 0 | 0 | 1 | 17 | 1 | 1 | 3.25 |
| SP | Scherzer, M.Scherzer, Max >> | 38 | 2022 | R | 89 | 27 | 27 | 9 | 11 | 3.51 | .294 | 1.21 | 8.4 | 2.6 | 7.8 | 197.2 | 183 | 77 | 77 | 30 | 57 | 170 | 5 | 0 | 0 | 0 | 17 | 7 | 1 | 4.23 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 68 | 26 | 26 | 11 | 10 | 3.63 | .298 | 1.25 | 6.9 | 4.3 | 7.9 | 188.1 | 145 | 78 | 76 | 21 | 90 | 165 | 4 | 0 | 0 | 2 | 16 | 5 | 2 | 4.21 |
| SP | Harvey, M.Harvey, Matt † >> | 24 | 2013 | R | 79 | 26 | 26 | 14 | 9 | 3.59 | .280 | 1.16 | 7.8 | 2.7 | 8.4 | 195.1 | 168 | 79 | 78 | 19 | 58 | 183 | 8 | 0 | 0 | 4 | 12 | 2 | 3 | 3.31 |
| SP | Martinez, P.Martinez, Pedro >> | 34 | 2005 | R | 77 | 26 | 26 | 11 | 14 | 4.04 | .310 | 1.35 | 9.1 | 3.0 | 6.0 | 194.0 | 196 | 95 | 87 | 21 | 65 | 129 | 10 | 0 | 0 | 2 | 13 | 1 | 5 | 4.10 |
| RP | Núnez, D.Núnez, Dedniel >> | 28 | 2024 | R | 58 | 48 | 0 | 2 | 1 | 1.09 | .253 | 1.02 | 6.8 | 2.4 | 10.8 | 41.1 | 31 | 7 | 5 | 3 | 11 | 49 | 0 | 6 | 0 | 0 | 0 | 0 | 1 | 2.37 |
| RP | Verrett, L.Verrett, Logan >> | 25 | 2015 | R | 64 | 54 | 0 | 3 | 2 | 2.79 | .227 | 0.88 | 5.9 | 2.0 | 8.1 | 58.0 | 38 | 18 | 18 | 5 | 13 | 52 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Wagner, B.Wagner, Billy >> | 37 | 2008 | L | 60 | 45 | 0 | 1 | 1 | 2.13 | .248 | 0.99 | 5.4 | 3.6 | 6.8 | 25.1 | 15 | 7 | 6 | 3 | 10 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.24 |
| RP | Robles, H.Robles, Hansel >> | 24 | 2015 | R | 47 | 19 | 0 | 1 | 3 | 4.50 | .277 | 1.10 | 7.2 | 2.7 | 8.6 | 20.0 | 16 | 10 | 10 | 4 | 6 | 19 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.75 |