| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 74 | 6 | 6 | 4 | 1 | 2.92 | .315 | 1.38 | 8.3 | 4.1 | 8.5 | 37.0 | 34 | 12 | 12 | 2 | 17 | 35 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 3.19 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 80 | 6 | 6 | 1 | 3 | 3.40 | .291 | 1.20 | 7.9 | 3.0 | 9.4 | 42.1 | 37 | 16 | 16 | 1 | 14 | 44 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 2.29 |
| SP | Strahm, M.Strahm, Matt >> | 26 | 2018 | L | 90 | 5 | 5 | 1 | 1 | 1.98 | .226 | 0.88 | 6.2 | 2.1 | 13.8 | 13.2 | 9 | 3 | 3 | 1 | 3 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.62 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 77 | 5 | 5 | 2 | 1 | 2.90 | .268 | 1.10 | 8.4 | 1.5 | 8.1 | 31.0 | 29 | 12 | 10 | 1 | 5 | 28 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 2.10 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 94 | 19 | 0 | 0 | 1 | 2.08 | .268 | 1.10 | 6.4 | 3.7 | 9.0 | 17.1 | 12 | 4 | 4 | 1 | 7 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 62 | 20 | 0 | 0 | 0 | 4.15 | .339 | 1.54 | 11.1 | 2.8 | 6.2 | 13.0 | 16 | 7 | 6 | 1 | 4 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.54 |
| RP | Hoffman, T.Hoffman, Trevor >> | 29 | 1996 | R | 63 | 12 | 0 | 1 | 1 | 3.52 | .313 | 1.30 | 10.8 | 1.2 | 9.0 | 15.1 | 18 | 6 | 6 | 1 | 2 | 15 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 2.47 |
| RP | Meredith, C.Meredith, Cla >> | 23 | 2006 | R | 80 | 9 | 0 | 2 | 1 | 2.08 | .235 | 0.92 | 6.8 | 2.3 | 5.6 | 8.2 | 6 | 2 | 2 | 1 | 2 | 5 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.13 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 88 | 3 | 0 | 0 | 1 | 2.70 | .286 | 1.20 | 9.0 | 3.0 | 3.0 | 3.1 | 3 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 77 | 3 | 0 | 0 | 0 | 3.60 | .318 | 1.40 | 12.6 | 0.0 | 9.0 | 5.0 | 7 | 2 | 2 | 1 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.60 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 3 | 0 | 0 | 0 | 3.38 | .200 | 0.75 | 4.5 | 4.5 | 0.0 | 2.2 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |