| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 74 | 34 | 34 | 17 | 8 | 2.86 | .284 | 1.19 | 6.9 | 3.8 | 8.2 | 214.1 | 164 | 68 | 68 | 17 | 91 | 195 | 1 | 0 | 0 | 1 | 25 | 0 | 9 | 3.49 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 80 | 33 | 33 | 10 | 13 | 3.51 | .261 | 1.04 | 6.9 | 2.5 | 9.5 | 223.1 | 170 | 88 | 87 | 29 | 63 | 235 | 4 | 0 | 0 | 0 | 24 | 4 | 3 | 3.48 |
| SP | Strahm, M.Strahm, Matt >> | 26 | 2018 | L | 90 | 33 | 32 | 1 | 4 | 2.78 | .262 | 1.05 | 6.6 | 2.9 | 8.7 | 71.1 | 52 | 22 | 22 | 3 | 23 | 69 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2.62 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 77 | 32 | 31 | 12 | 11 | 3.19 | .280 | 1.15 | 7.5 | 2.9 | 8.0 | 186.0 | 154 | 73 | 66 | 18 | 60 | 165 | 0 | 1 | 0 | 0 | 18 | 3 | 5 | 3.50 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 94 | 103 | 0 | 8 | 2 | 3.26 | .269 | 1.09 | 6.8 | 3.1 | 9.5 | 116.0 | 87 | 42 | 42 | 13 | 40 | 123 | 0 | 8 | 5 | 0 | 0 | 1 | 2 | 3.40 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 62 | 115 | 0 | 4 | 2 | 2.46 | .261 | 1.05 | 7.6 | 1.8 | 7.7 | 84.0 | 71 | 24 | 23 | 4 | 17 | 72 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 2.55 |
| RP | Hoffman, T.Hoffman, Trevor >> | 29 | 1996 | R | 63 | 74 | 0 | 7 | 5 | 3.35 | .305 | 1.30 | 7.8 | 4.0 | 9.4 | 96.2 | 83 | 37 | 36 | 7 | 43 | 100 | 0 | 10 | 3 | 0 | 0 | 1 | 3 | 3.24 |
| RP | Meredith, C.Meredith, Cla >> | 23 | 2006 | R | 80 | 58 | 0 | 6 | 2 | 1.51 | .221 | 0.85 | 6.0 | 1.8 | 5.2 | 71.2 | 47 | 12 | 12 | 6 | 14 | 41 | 0 | 10 | 2 | 0 | 0 | 0 | 0 | 3.54 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 88 | 36 | 0 | 5 | 1 | 1.83 | .249 | 0.95 | 5.3 | 3.3 | 6.3 | 44.1 | 26 | 9 | 9 | 3 | 16 | 31 | 0 | 6 | 1 | 0 | 0 | 2 | 2 | 3.70 |
| RP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 77 | 28 | 0 | 0 | 3 | 2.77 | .287 | 1.21 | 7.8 | 3.0 | 8.5 | 39.0 | 34 | 12 | 12 | 2 | 13 | 37 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 2.77 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 24 | 0 | 1 | 2 | 2.43 | .226 | 0.88 | 5.0 | 3.1 | 7.8 | 29.2 | 16 | 8 | 8 | 2 | 10 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.21 |