| SP | Liriano, F.Liriano, Francisco $ >> | 23 | 2006 | L | 98 | 8 | 8 | 3 | 1 | 3.96 | .310 | 1.35 | 8.5 | 3.8 | 8.5 | 36.1 | 34 | 16 | 16 | 5 | 15 | 34 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 4.17 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 8 | 8 | 4 | 1 | 3.86 | .280 | 1.17 | 7.8 | 2.8 | 8.3 | 51.1 | 44 | 22 | 22 | 9 | 16 | 47 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 4.39 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 73 | 8 | 8 | 1 | 2 | 9.23 | .378 | 1.75 | 13.5 | 2.4 | 6.2 | 26.1 | 39 | 27 | 27 | 10 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 7.65 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 66 | 8 | 8 | 1 | 3 | 6.98 | .365 | 1.68 | 11.3 | 3.8 | 5.9 | 40.0 | 50 | 39 | 31 | 8 | 17 | 26 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5.73 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 54 | 8 | 8 | 0 | 3 | 6.64 | .393 | 1.92 | 12.4 | 5.2 | 7.4 | 40.2 | 55 | 37 | 30 | 7 | 23 | 33 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 5.43 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 66 | 24 | 0 | 3 | 2 | 4.76 | .325 | 1.41 | 10.6 | 2.3 | 5.5 | 28.1 | 33 | 15 | 15 | 6 | 7 | 17 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.43 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 67 | 24 | 0 | 0 | 1 | 6.39 | .356 | 1.58 | 11.9 | 2.5 | 8.3 | 25.1 | 33 | 20 | 18 | 3 | 7 | 23 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.80 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 64 | 26 | 0 | 2 | 0 | 1.05 | .206 | 0.74 | 4.0 | 2.9 | 6.5 | 25.2 | 11 | 3 | 3 | 0 | 8 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.64 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 62 | 19 | 0 | 4 | 1 | 3.86 | .197 | 0.67 | 5.1 | 1.1 | 7.3 | 16.1 | 9 | 7 | 7 | 4 | 2 | 13 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 5.19 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 85 | 17 | 0 | 2 | 0 | 4.73 | .365 | 1.73 | 9.0 | 6.9 | 9.7 | 13.1 | 13 | 7 | 7 | 1 | 10 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.15 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 81 | 7 | 0 | 3 | 0 | 1.42 | .174 | 0.63 | 6.0 | 0.0 | 5.3 | 12.2 | 8 | 2 | 2 | 1 | 0 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.92 |
| CL | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 19 | 0 | 1 | 0 | 2.17 | .269 | 1.03 | 6.2 | 3.1 | 9.9 | 29.0 | 20 | 7 | 7 | 2 | 10 | 32 | 0 | 5 | 0 | 0 | 0 | 2 | 0 | 2.93 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 17 | 0 | 2 | 0 | 2.95 | .313 | 1.31 | 8.5 | 3.5 | 9.5 | 18.1 | 17 | 6 | 6 | 0 | 7 | 19 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.22 |