| SP | Schmidt, J.Schmidt, Jason $ >> | 30 | 2003 | R | 99 | 21 | 21 | 5 | 8 | 4.33 | .306 | 1.29 | 9.1 | 2.6 | 8.2 | 141.1 | 143 | 74 | 68 | 21 | 40 | 128 | 2 | 0 | 0 | 0 | 11 | 4 | 2 | 4.06 |
| SP | Peavy, J.Peavy, Jake † # >> | 26 | 2007 | R | 89 | 20 | 20 | 11 | 3 | 4.18 | .306 | 1.28 | 8.7 | 2.8 | 8.8 | 125.0 | 121 | 61 | 58 | 18 | 39 | 122 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 3.98 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 77 | 19 | 19 | 7 | 7 | 4.61 | .321 | 1.40 | 9.9 | 2.7 | 9.2 | 127.0 | 140 | 66 | 65 | 13 | 38 | 130 | 1 | 0 | 0 | 0 | 8 | 2 | 4 | 3.23 |
| SU | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 36 | 0 | 3 | 0 | 3.63 | .274 | 1.08 | 6.5 | 3.5 | 10.2 | 39.2 | 28 | 16 | 16 | 4 | 15 | 44 | 0 | 2 | 4 | 0 | 0 | 2 | 1 | 3.38 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 56 | 0 | 3 | 0 | 1.71 | .243 | 0.95 | 6.4 | 2.2 | 8.8 | 58.0 | 41 | 13 | 11 | 4 | 14 | 57 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 2.71 |
| RP | Shields, S.Shields, Scot >> | 30 | 2005 | R | 31 | 31 | 0 | 2 | 0 | 3.90 | .348 | 1.57 | 9.0 | 5.1 | 9.9 | 30.0 | 30 | 13 | 13 | 7 | 17 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.63 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 33 | 36 | 0 | 1 | 3 | 4.43 | .282 | 1.13 | 7.2 | 3.2 | 10.8 | 20.1 | 16 | 10 | 10 | 2 | 7 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.10 |
| RP | Smoltz, J.Smoltz, John $ >> | 36 | 2003 | R | 75 | 27 | 0 | 3 | 2 | 5.61 | .280 | 1.17 | 9.0 | 1.8 | 10.8 | 25.2 | 25 | 18 | 16 | 4 | 5 | 30 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 35 | 0 | 0 | 0 | 3.04 | .324 | 1.39 | 8.2 | 4.7 | 11.0 | 23.2 | 21 | 8 | 8 | 1 | 12 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.83 |