| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 14 | 14 | 5 | 6 | 5.14 | .332 | 1.47 | 9.4 | 3.8 | 8.0 | 89.1 | 93 | 52 | 51 | 19 | 38 | 79 | 1 | 0 | 0 | 0 | 7 | 2 | 2 | 5.35 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 80 | 13 | 13 | 5 | 3 | 3.59 | .305 | 1.29 | 8.7 | 3.1 | 9.1 | 82.2 | 79 | 34 | 33 | 13 | 28 | 83 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 4.13 |
| SP | Hamels, C.Hamels, Cole # >> | 25 | 2008 | L | 72 | 13 | 13 | 6 | 4 | 4.07 | .278 | 1.11 | 8.3 | 1.7 | 6.5 | 84.0 | 77 | 38 | 38 | 17 | 16 | 61 | 0 | 0 | 0 | 0 | 9 | 4 | 0 | 4.89 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 13 | 13 | 7 | 2 | 4.36 | .312 | 1.32 | 9.3 | 2.7 | 6.8 | 84.2 | 87 | 41 | 41 | 14 | 25 | 63 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.67 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 49 | 13 | 13 | 5 | 5 | 5.45 | .347 | 1.55 | 9.7 | 4.3 | 5.8 | 76.0 | 82 | 47 | 46 | 13 | 36 | 49 | 0 | 0 | 0 | 0 | 6 | 3 | 3 | 5.47 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 34 | 0 | 1 | 1 | 3.00 | .289 | 1.19 | 5.8 | 5.0 | 8.5 | 36.0 | 23 | 13 | 12 | 5 | 20 | 34 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 4.67 |
| RP | Williamson, S.Williamson, Scott >> | 26 | 2002 | R | 51 | 25 | 0 | 1 | 2 | 6.23 | .372 | 1.71 | 9.0 | 6.6 | 6.3 | 30.1 | 30 | 21 | 21 | 3 | 22 | 21 | 0 | 3 | 1 | 0 | 0 | 2 | 3 | 5.30 |
| RP | Guerrier, M.Guerrier, Matt >> | 31 | 2009 | R | 41 | 17 | 0 | 0 | 2 | 4.24 | .255 | 1.03 | 5.9 | 3.5 | 5.5 | 23.1 | 15 | 11 | 11 | 3 | 9 | 14 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.65 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 31 | 13 | 0 | 3 | 0 | 4.86 | .367 | 1.74 | 14.6 | 1.7 | 11.3 | 16.2 | 26 | 9 | 9 | 4 | 3 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.31 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 45 | 5 | 0 | 0 | 1 | 4.38 | .288 | 1.22 | 8.3 | 3.0 | 8.3 | 12.1 | 11 | 6 | 6 | 1 | 4 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.25 |