| SP | Hernandez, F.Hernandez, Felix $ >> | 19 | 2005 | R | 96 | 18 | 18 | 3 | 7 | 5.20 | .325 | 1.42 | 9.0 | 3.8 | 5.8 | 114.1 | 114 | 69 | 66 | 18 | 48 | 74 | 2 | 0 | 0 | 0 | 7 | 3 | 0 | 5.10 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 81 | 16 | 16 | 4 | 6 | 5.67 | .317 | 1.36 | 8.7 | 3.5 | 8.7 | 92.0 | 89 | 62 | 58 | 14 | 36 | 89 | 0 | 0 | 0 | 0 | 5 | 3 | 2 | 4.32 |
| SP | Greinke, Z.Greinke, Zack # >> | 26 | 2009 | R | 77 | 17 | 17 | 9 | 7 | 3.73 | .296 | 1.22 | 8.3 | 2.7 | 9.6 | 111.0 | 102 | 48 | 46 | 14 | 33 | 119 | 1 | 0 | 0 | 0 | 11 | 5 | 3 | 3.52 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 17 | 17 | 3 | 9 | 5.03 | .342 | 1.52 | 10.3 | 3.4 | 6.1 | 107.1 | 123 | 66 | 60 | 18 | 40 | 73 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 5.06 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 71 | 17 | 17 | 4 | 11 | 5.77 | .348 | 1.59 | 9.8 | 4.6 | 5.9 | 96.2 | 105 | 68 | 62 | 15 | 49 | 63 | 1 | 0 | 0 | 0 | 7 | 1 | 2 | 5.28 |
| CL | Nathan, J.Nathan, Joe † $ >> | 32 | 2006 | R | 98 | 30 | 0 | 3 | 2 | 3.86 | .341 | 1.52 | 9.0 | 4.8 | 11.7 | 30.1 | 30 | 13 | 13 | 3 | 16 | 39 | 0 | 18 | 4 | 0 | 0 | 1 | 1 | 3.40 |
| SU | Percival, T.Percival, Troy >> | 38 | 2007 | R | 85 | 30 | 0 | 1 | 1 | 4.45 | .297 | 1.27 | 7.3 | 4.2 | 8.2 | 32.1 | 26 | 19 | 16 | 3 | 15 | 29 | 0 | 5 | 6 | 0 | 0 | 0 | 2 | 3.81 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 84 | 36 | 0 | 3 | 1 | 3.72 | .284 | 1.16 | 6.9 | 3.8 | 10.7 | 38.2 | 29 | 17 | 16 | 4 | 16 | 45 | 0 | 0 | 1 | 0 | 0 | 1 | 5 | 3.34 |
| RP | Gordon, T.Gordon, Tom $$ >> | 37 | 2004 | R | 81 | 35 | 0 | 4 | 1 | 3.12 | .288 | 1.21 | 7.0 | 4.1 | 8.6 | 40.1 | 31 | 14 | 14 | 6 | 18 | 38 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.40 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 24 | 0 | 2 | 2 | 2.52 | .272 | 1.12 | 8.3 | 1.8 | 9.7 | 25.0 | 23 | 8 | 7 | 2 | 5 | 27 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2.48 |