| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 11 | 11 | 7 | 2 | 2.28 | .275 | 1.13 | 6.5 | 3.6 | 9.9 | 79.0 | 57 | 21 | 20 | 9 | 32 | 87 | 2 | 0 | 0 | 1 | 9 | 1 | 3 | 3.53 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 86 | 12 | 12 | 1 | 5 | 5.93 | .347 | 1.55 | 9.8 | 4.1 | 7.0 | 44.0 | 48 | 30 | 29 | 8 | 20 | 34 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.32 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 64 | 12 | 12 | 3 | 7 | 4.02 | .313 | 1.30 | 9.0 | 2.8 | 4.5 | 78.1 | 78 | 37 | 35 | 14 | 24 | 39 | 1 | 0 | 0 | 0 | 6 | 5 | 0 | 5.45 |
| SP | Patterson, J.Patterson, John # >> | 27 | 2005 | R | 34 | 13 | 12 | 3 | 6 | 4.29 | .310 | 1.29 | 8.2 | 3.4 | 9.0 | 71.1 | 65 | 36 | 34 | 8 | 27 | 71 | 1 | 0 | 0 | 1 | 4 | 4 | 3 | 3.77 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 34 | 0 | 2 | 2 | 3.00 | .298 | 1.25 | 7.1 | 4.1 | 9.4 | 48.0 | 38 | 20 | 16 | 6 | 22 | 50 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 3.98 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 28 | 2002 | R | 47 | 25 | 0 | 1 | 3 | 6.08 | .350 | 1.61 | 9.7 | 5.2 | 8.3 | 26.2 | 28 | 18 | 18 | 4 | 15 | 24 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.88 |
| RP | Kim, B.Kim, Byung-Hyun >> | 23 | 2002 | R | 34 | 23 | 0 | 0 | 0 | 4.15 | .339 | 1.54 | 8.3 | 5.5 | 11.1 | 26.0 | 24 | 15 | 12 | 4 | 16 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 4.38 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 25 | 2001 | R | 21 | 22 | 0 | 2 | 1 | 3.55 | .315 | 1.38 | 9.0 | 3.6 | 11.5 | 25.1 | 25 | 10 | 10 | 7 | 10 | 32 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 5.28 |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 23 | 17 | 1 | 1 | 5 | 5.28 | .374 | 1.79 | 12.1 | 4.0 | 4.3 | 29.0 | 39 | 19 | 17 | 7 | 13 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 6.52 |