| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 13 | 13 | 5 | 5 | 3.78 | .294 | 1.23 | 7.8 | 3.3 | 8.0 | 88.0 | 76 | 37 | 37 | 7 | 32 | 78 | 1 | 0 | 0 | 1 | 9 | 2 | 2 | 3.42 |
| SP | Hamels, C.Hamels, Cole # >> | 25 | 2008 | L | 72 | 12 | 12 | 4 | 3 | 5.13 | .327 | 1.43 | 10.5 | 2.4 | 5.6 | 79.0 | 92 | 45 | 45 | 14 | 21 | 49 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 4.94 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 52 | 12 | 12 | 2 | 4 | 5.47 | .340 | 1.49 | 9.6 | 3.9 | 5.3 | 72.1 | 77 | 44 | 44 | 7 | 31 | 42 | 0 | 0 | 0 | 0 | 5 | 4 | 2 | 4.56 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 70 | 32 | 0 | 2 | 4 | 3.22 | .268 | 1.05 | 7.6 | 2.0 | 7.6 | 44.2 | 37 | 16 | 16 | 1 | 10 | 37 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 2.43 |
| RP | Williamson, S.Williamson, Scott >> | 26 | 2002 | R | 50 | 24 | 0 | 1 | 3 | 8.16 | .381 | 1.85 | 11.6 | 5.5 | 8.7 | 28.2 | 36 | 26 | 26 | 8 | 17 | 27 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6.61 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 38 | 26 | 0 | 1 | 3 | 8.14 | .397 | 1.93 | 12.4 | 5.3 | 7.5 | 24.1 | 33 | 25 | 22 | 6 | 14 | 20 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 6.46 |
| SP | Appier, K.Appier, Kevin >> | 34 | 2001 | R | 38 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 49 | 16 | 0 | 1 | 2 | 8.63 | .400 | 2.00 | 15.8 | 2.3 | 5.6 | 24.0 | 42 | 24 | 23 | 5 | 6 | 15 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.21 |