| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 14 | 14 | 7 | 5 | 3.82 | .309 | 1.33 | 7.7 | 4.3 | 8.5 | 75.1 | 64 | 34 | 32 | 10 | 36 | 71 | 0 | 0 | 0 | 0 | 6 | 1 | 2 | 4.32 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 85 | 14 | 14 | 5 | 5 | 4.19 | .322 | 1.39 | 9.8 | 2.7 | 6.2 | 101.0 | 110 | 49 | 47 | 14 | 30 | 70 | 3 | 0 | 0 | 1 | 7 | 4 | 1 | 4.43 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 13 | 13 | 9 | 2 | 3.73 | .309 | 1.30 | 8.9 | 2.9 | 6.0 | 82.0 | 81 | 34 | 34 | 10 | 26 | 55 | 0 | 0 | 0 | 0 | 8 | 3 | 0 | 4.30 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 13 | 13 | 6 | 5 | 5.59 | .351 | 1.57 | 10.3 | 3.8 | 7.9 | 74.0 | 85 | 49 | 46 | 17 | 31 | 65 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 5.65 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 88 | 42 | 0 | 3 | 0 | 2.64 | .240 | 0.91 | 6.7 | 1.6 | 9.0 | 58.0 | 43 | 17 | 17 | 5 | 10 | 58 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 2.74 |
| RP | Springer, R.Springer, Russ # >> | 39 | 2007 | R | 78 | 30 | 0 | 3 | 1 | 5.77 | .322 | 1.43 | 9.0 | 4.0 | 8.7 | 34.1 | 34 | 22 | 22 | 3 | 15 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.53 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 66 | 21 | 0 | 1 | 0 | 4.50 | .294 | 1.17 | 5.6 | 4.9 | 6.0 | 24.0 | 15 | 12 | 12 | 3 | 13 | 16 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 5.17 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 16 | 0 | 0 | 0 | 5.17 | .338 | 1.47 | 9.6 | 4.2 | 9.0 | 15.2 | 16 | 9 | 9 | 3 | 7 | 15 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.20 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 31 | 17 | 0 | 0 | 2 | 6.00 | .370 | 1.71 | 10.7 | 4.7 | 10.7 | 21.0 | 25 | 14 | 14 | 6 | 11 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 6.05 |
| CL | Gagne, E.Gagne, Eric $ >> | 27 | 2003 | R | 100 | 29 | 0 | 1 | 1 | 1.07 | .235 | 0.92 | 5.5 | 3.0 | 12.0 | 33.2 | 20 | 4 | 4 | 0 | 11 | 44 | 0 | 17 | 1 | 0 | 0 | 0 | 1 | 1.33 |