| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 18 | 18 | 6 | 5 | 3.93 | .340 | 1.52 | 8.0 | 5.8 | 10.4 | 89.1 | 79 | 41 | 39 | 10 | 57 | 103 | 0 | 0 | 0 | 0 | 2 | 2 | 3 | 4.13 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 86 | 18 | 18 | 5 | 6 | 4.36 | .310 | 1.32 | 8.1 | 3.9 | 6.0 | 107.1 | 96 | 55 | 52 | 12 | 46 | 71 | 1 | 0 | 0 | 0 | 9 | 3 | 2 | 4.50 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 18 | 17 | 3 | 10 | 7.46 | .363 | 1.67 | 11.0 | 4.0 | 6.5 | 76.0 | 93 | 65 | 63 | 19 | 34 | 55 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 6.26 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 61 | 20 | 17 | 9 | 6 | 3.86 | .311 | 1.34 | 9.2 | 2.9 | 7.9 | 119.0 | 121 | 52 | 51 | 13 | 38 | 104 | 4 | 0 | 0 | 1 | 12 | 2 | 2 | 3.68 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 94 | 61 | 0 | 6 | 3 | 3.36 | .279 | 1.16 | 7.6 | 3.0 | 8.7 | 69.2 | 58 | 28 | 26 | 8 | 23 | 67 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 3.57 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 51 | 0 | 2 | 2 | 3.06 | .289 | 1.22 | 7.0 | 4.1 | 11.0 | 64.2 | 50 | 22 | 22 | 8 | 29 | 78 | 0 | 5 | 1 | 0 | 0 | 0 | 2 | 3.55 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 42 | 0 | 3 | 1 | 4.50 | .299 | 1.22 | 7.6 | 3.3 | 11.7 | 46.0 | 39 | 24 | 23 | 6 | 17 | 60 | 0 | 4 | 1 | 0 | 0 | 3 | 3 | 3.39 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 63 | 57 | 0 | 3 | 1 | 4.67 | .362 | 1.63 | 10.5 | 4.2 | 7.5 | 54.0 | 63 | 34 | 28 | 8 | 25 | 45 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 4.87 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 43 | 0 | 2 | 2 | 3.94 | .332 | 1.49 | 6.0 | 7.6 | 9.2 | 45.2 | 30 | 23 | 20 | 2 | 38 | 46 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 4.07 |