| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 29 | 29 | 13 | 9 | 3.75 | .297 | 1.25 | 7.9 | 3.3 | 9.7 | 197.0 | 173 | 89 | 82 | 24 | 73 | 212 | 2 | 0 | 0 | 1 | 15 | 4 | 7 | 3.60 |
| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 81 | 28 | 28 | 11 | 9 | 4.10 | .306 | 1.29 | 8.7 | 2.9 | 9.5 | 182.0 | 175 | 88 | 83 | 23 | 59 | 193 | 2 | 0 | 0 | 1 | 14 | 7 | 1 | 3.61 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 68 | 28 | 28 | 10 | 9 | 4.64 | .325 | 1.42 | 10.1 | 2.8 | 5.4 | 186.1 | 208 | 107 | 96 | 31 | 57 | 112 | 1 | 0 | 0 | 1 | 14 | 4 | 6 | 4.95 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 49 | 27 | 26 | 13 | 6 | 3.89 | .284 | 1.16 | 7.9 | 2.6 | 6.1 | 173.1 | 151 | 78 | 75 | 22 | 50 | 118 | 2 | 0 | 0 | 2 | 14 | 5 | 2 | 4.24 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 89 | 70 | 0 | 6 | 2 | 4.63 | .300 | 1.28 | 7.6 | 3.9 | 8.8 | 89.1 | 75 | 46 | 46 | 18 | 39 | 87 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 5.02 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 57 | 0 | 4 | 2 | 3.77 | .314 | 1.32 | 9.6 | 2.3 | 10.9 | 62.0 | 66 | 28 | 26 | 4 | 16 | 75 | 0 | 1 | 4 | 0 | 0 | 3 | 0 | 2.34 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 56 | 31 | 0 | 2 | 2 | 2.62 | .280 | 1.17 | 6.6 | 4.0 | 8.7 | 34.1 | 25 | 12 | 10 | 4 | 15 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.91 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 100 | 56 | 0 | 7 | 3 | 1.81 | .242 | 0.94 | 5.9 | 2.7 | 10.3 | 64.2 | 42 | 17 | 13 | 5 | 19 | 73 | 0 | 32 | 5 | 0 | 0 | 1 | 0 | 2.67 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 60 | 6 | 1 | 0 | 3 | 6.39 | .309 | 1.34 | 12.0 | 0.8 | 4.5 | 12.2 | 16 | 9 | 9 | 1 | 1 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.33 |