| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 25 | 25 | 6 | 8 | 3.60 | .274 | 1.09 | 7.0 | 2.9 | 10.2 | 157.1 | 122 | 64 | 63 | 17 | 50 | 178 | 1 | 0 | 0 | 1 | 18 | 6 | 3 | 3.21 |
| SP | Nelson, R.Nelson, Ryne # >> | 27 | 2025 | R | 81 | 24 | 24 | 4 | 10 | 5.88 | .341 | 1.50 | 10.0 | 3.6 | 6.8 | 113.1 | 125 | 77 | 74 | 16 | 45 | 86 | 0 | 0 | 0 | 0 | 4 | 6 | 3 | 4.67 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 65 | 24 | 24 | 4 | 10 | 5.72 | .348 | 1.58 | 10.6 | 3.6 | 6.8 | 137.0 | 161 | 88 | 87 | 28 | 55 | 103 | 1 | 0 | 0 | 0 | 9 | 3 | 4 | 5.42 |
| SP | Burrows, M.Burrows, Mike # >> | 25 | 2025 | R | 62 | 23 | 23 | 2 | 10 | 5.52 | .322 | 1.38 | 9.1 | 3.3 | 10.4 | 101.0 | 102 | 62 | 62 | 14 | 37 | 117 | 0 | 0 | 0 | 0 | 1 | 5 | 3 | 3.73 |
| RP | Okert, S.Okert, Steven >> | 33 | 2025 | L | 97 | 59 | 0 | 9 | 3 | 3.19 | .291 | 1.22 | 6.4 | 4.6 | 9.6 | 84.2 | 60 | 31 | 30 | 9 | 43 | 90 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 3.82 |
| RP | Bazardo, E.Bazardo, Eduard >> | 29 | 2025 | R | 86 | 64 | 0 | 5 | 5 | 3.20 | .341 | 1.55 | 9.6 | 4.4 | 9.4 | 84.1 | 90 | 32 | 30 | 14 | 41 | 88 | 0 | 6 | 3 | 0 | 0 | 0 | 1 | 4.54 |
| RP | Strahm, M.Strahm, Matt >> | 33 | 2025 | L | 73 | 62 | 0 | 2 | 5 | 3.87 | .303 | 1.25 | 7.0 | 4.3 | 10.9 | 81.1 | 63 | 37 | 35 | 6 | 39 | 98 | 0 | 4 | 4 | 0 | 0 | 4 | 3 | 3.14 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 63 | 61 | 0 | 5 | 4 | 2.53 | .238 | 0.90 | 6.1 | 2.1 | 9.2 | 74.2 | 50 | 22 | 21 | 6 | 17 | 76 | 0 | 4 | 1 | 0 | 0 | 3 | 5 | 2.81 |
| SP | Giolito, L.Giolito, Lucas >> | 30 | 2025 | R | 46 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Priester, Q.Priester, Quinn >> | 24 | 2025 | R | 53 | 1 | 0 | 0 | 0 | 0.00 | .357 | 1.67 | 6.0 | 9.0 | 9.0 | 3.0 | 2 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |