| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 10 | 13 | 3.86 | .278 | 1.16 | 8.2 | 2.2 | 9.0 | 221.1 | 201 | 99 | 95 | 26 | 55 | 222 | 1 | 0 | 0 | 0 | 22 | 0 | 0 | 3.27 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 33 | 33 | 13 | 15 | 4.24 | .290 | 1.21 | 8.0 | 2.9 | 8.9 | 250.1 | 223 | 123 | 118 | 38 | 80 | 246 | 11 | 0 | 0 | 1 | 17 | 4 | 3 | 4.02 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 32 | 32 | 11 | 17 | 5.85 | .353 | 1.63 | 11.0 | 3.7 | 4.2 | 201.2 | 246 | 148 | 131 | 27 | 83 | 94 | 4 | 0 | 0 | 2 | 10 | 1 | 5 | 5.06 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 32 | 32 | 12 | 11 | 5.29 | .332 | 1.46 | 10.2 | 2.9 | 5.5 | 211.0 | 240 | 130 | 124 | 29 | 69 | 128 | 7 | 0 | 0 | 3 | 11 | 5 | 4 | 4.63 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 31 | 9 | 10 | 4.23 | .332 | 1.48 | 9.8 | 3.5 | 4.5 | 208.1 | 227 | 108 | 98 | 28 | 81 | 103 | 2 | 0 | 0 | 0 | 18 | 2 | 4 | 4.96 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 78 | 0 | 3 | 3 | 3.79 | .287 | 1.18 | 8.0 | 2.6 | 9.4 | 92.2 | 82 | 39 | 39 | 12 | 27 | 96 | 0 | 8 | 6 | 0 | 0 | 3 | 2 | 3.59 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 60 | 0 | 6 | 4 | 4.00 | .274 | 1.12 | 8.1 | 2.1 | 8.0 | 69.2 | 62 | 33 | 31 | 12 | 16 | 61 | 0 | 7 | 1 | 0 | 0 | 1 | 0 | 4.23 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 28 | 0 | 1 | 1 | 1.13 | .256 | 1.00 | 6.2 | 2.8 | 7.0 | 32.0 | 22 | 8 | 4 | 3 | 10 | 25 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.69 |