| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 34 | 34 | 12 | 17 | 4.63 | .299 | 1.24 | 8.7 | 2.5 | 8.2 | 221.2 | 213 | 119 | 114 | 32 | 62 | 202 | 5 | 0 | 0 | 2 | 18 | 8 | 3 | 4.00 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 32 | 32 | 11 | 14 | 4.59 | .307 | 1.32 | 9.4 | 2.5 | 5.5 | 225.2 | 234 | 134 | 115 | 32 | 63 | 138 | 11 | 0 | 0 | 1 | 13 | 3 | 4 | 4.50 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 33 | 31 | 8 | 12 | 5.05 | .353 | 1.62 | 10.6 | 4.0 | 8.3 | 196.0 | 231 | 131 | 110 | 33 | 87 | 180 | 0 | 0 | 0 | 0 | 14 | 3 | 8 | 4.73 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 83 | 0 | 7 | 4 | 4.01 | .286 | 1.19 | 7.8 | 3.0 | 8.7 | 112.1 | 97 | 52 | 50 | 11 | 37 | 108 | 0 | 6 | 4 | 0 | 0 | 1 | 2 | 3.37 |
| RP | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 93 | 70 | 0 | 7 | 0 | 1.81 | .246 | 0.97 | 4.4 | 4.4 | 10.5 | 84.2 | 41 | 18 | 17 | 4 | 41 | 98 | 0 | 11 | 0 | 0 | 0 | 1 | 7 | 2.79 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 37 | 0 | 1 | 4 | 2.51 | .267 | 1.09 | 8.6 | 1.4 | 7.4 | 46.2 | 44 | 15 | 13 | 6 | 7 | 38 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 30 | 0 | 1 | 1 | 5.63 | .314 | 1.38 | 7.3 | 5.1 | 11.0 | 32.0 | 26 | 25 | 20 | 7 | 18 | 39 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 5.09 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 28 | 0 | 0 | 2 | 7.43 | .385 | 1.84 | 11.4 | 5.5 | 10.0 | 26.2 | 33 | 23 | 22 | 9 | 16 | 29 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 7.23 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 10 | 0 | 0 | 1 | 20.86 | .532 | 3.41 | 25.7 | 6.4 | 10.3 | 7.1 | 20 | 17 | 17 | 1 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.71 |