| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 24 | 24 | 11 | 7 | 3.63 | .291 | 1.23 | 8.4 | 2.7 | 9.9 | 161.1 | 150 | 65 | 65 | 16 | 48 | 177 | 2 | 0 | 0 | 1 | 15 | 1 | 2 | 3.01 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 72 | 23 | 23 | 8 | 8 | 4.46 | .300 | 1.26 | 8.6 | 2.7 | 4.9 | 155.1 | 148 | 80 | 77 | 17 | 47 | 84 | 1 | 0 | 0 | 1 | 11 | 5 | 3 | 4.35 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 23 | 23 | 7 | 9 | 4.92 | .342 | 1.55 | 9.1 | 4.9 | 4.9 | 159.0 | 160 | 96 | 87 | 19 | 86 | 86 | 2 | 0 | 0 | 0 | 10 | 2 | 9 | 5.13 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 22 | 22 | 2 | 14 | 6.09 | .358 | 1.65 | 9.9 | 5.0 | 5.0 | 127.0 | 139 | 95 | 86 | 14 | 71 | 71 | 1 | 0 | 0 | 1 | 7 | 2 | 2 | 5.04 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 22 | 22 | 8 | 11 | 4.81 | .300 | 1.28 | 9.4 | 2.1 | 5.6 | 157.1 | 164 | 94 | 84 | 23 | 37 | 97 | 8 | 0 | 0 | 1 | 7 | 1 | 1 | 4.39 |
| RP | Uehara, K.Uehara, Koji # >> | 38 | 2013 | R | 100 | 62 | 0 | 2 | 5 | 4.98 | .313 | 1.35 | 8.7 | 3.5 | 7.3 | 65.0 | 63 | 39 | 36 | 14 | 25 | 53 | 0 | 4 | 5 | 0 | 0 | 1 | 1 | 5.37 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 51 | 0 | 6 | 1 | 5.40 | .352 | 1.58 | 9.5 | 4.8 | 8.7 | 58.1 | 61 | 35 | 35 | 8 | 31 | 56 | 0 | 5 | 3 | 0 | 0 | 3 | 5 | 4.62 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 18 | 0 | 2 | 0 | 8.44 | .340 | 1.55 | 11.6 | 2.6 | 9.4 | 21.1 | 27 | 20 | 20 | 8 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.71 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 24 | 0 | 1 | 0 | 7.17 | .390 | 1.92 | 13.3 | 4.3 | 7.7 | 21.1 | 31 | 17 | 17 | 5 | 10 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.81 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 9 | 0 | 3 | 0 | 2.29 | .272 | 1.12 | 6.6 | 3.8 | 3.3 | 19.2 | 14 | 8 | 5 | 2 | 8 | 7 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.89 |