| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 21 | 21 | 8 | 6 | 3.34 | .270 | 1.09 | 7.5 | 2.4 | 8.5 | 148.0 | 123 | 55 | 55 | 16 | 39 | 140 | 3 | 0 | 0 | 1 | 14 | 2 | 3 | 3.34 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 20 | 20 | 10 | 4 | 3.05 | .280 | 1.15 | 7.4 | 3.0 | 8.3 | 135.2 | 111 | 50 | 46 | 19 | 45 | 125 | 0 | 0 | 0 | 0 | 17 | 2 | 1 | 4.02 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 20 | 19 | 8 | 7 | 3.73 | .289 | 1.21 | 9.0 | 1.9 | 3.1 | 128.0 | 128 | 58 | 53 | 14 | 27 | 44 | 6 | 0 | 0 | 1 | 11 | 1 | 2 | 4.39 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 21 | 19 | 5 | 6 | 5.83 | .341 | 1.52 | 10.5 | 3.3 | 4.8 | 105.0 | 122 | 74 | 68 | 17 | 38 | 56 | 0 | 1 | 0 | 0 | 6 | 3 | 0 | 5.21 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 48 | 0 | 3 | 1 | 3.51 | .289 | 1.20 | 7.5 | 3.4 | 7.8 | 59.0 | 49 | 24 | 23 | 6 | 22 | 51 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 3.76 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 44 | 0 | 2 | 5 | 3.61 | .308 | 1.32 | 6.8 | 5.2 | 8.1 | 52.1 | 39 | 21 | 21 | 5 | 30 | 47 | 0 | 3 | 1 | 0 | 0 | 1 | 4 | 4.23 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 40 | 0 | 1 | 5 | 7.01 | .361 | 1.67 | 11.1 | 4.2 | 8.8 | 43.2 | 53 | 36 | 34 | 8 | 20 | 42 | 0 | 5 | 2 | 0 | 0 | 1 | 1 | 4.93 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 30 | 0 | 3 | 2 | 6.62 | .321 | 1.42 | 10.3 | 2.6 | 9.0 | 35.1 | 40 | 27 | 26 | 11 | 10 | 35 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 5.94 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 10 | 0 | 2 | 3 | 5.49 | .359 | 1.63 | 10.9 | 4.3 | 2.4 | 19.2 | 23 | 12 | 12 | 3 | 9 | 5 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.11 |