| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 21 | 21 | 6 | 12 | 4.28 | .310 | 1.34 | 9.1 | 3.0 | 6.0 | 145.0 | 146 | 82 | 69 | 24 | 49 | 96 | 1 | 0 | 0 | 0 | 10 | 0 | 5 | 4.84 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 19 | 19 | 5 | 12 | 5.32 | .337 | 1.50 | 9.9 | 3.6 | 6.0 | 137.0 | 151 | 90 | 81 | 14 | 55 | 92 | 7 | 0 | 0 | 0 | 7 | 3 | 1 | 4.26 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 19 | 19 | 7 | 9 | 5.13 | .332 | 1.47 | 10.9 | 2.4 | 4.9 | 140.1 | 169 | 89 | 80 | 22 | 37 | 76 | 5 | 0 | 0 | 1 | 8 | 3 | 3 | 4.81 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 19 | 19 | 9 | 6 | 4.31 | .330 | 1.47 | 9.9 | 3.3 | 6.7 | 144.0 | 159 | 78 | 69 | 18 | 52 | 107 | 4 | 0 | 0 | 2 | 9 | 2 | 1 | 4.26 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 30 | 0 | 2 | 4 | 3.30 | .328 | 1.43 | 9.0 | 3.9 | 8.1 | 30.0 | 30 | 11 | 11 | 3 | 13 | 27 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 3.90 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 16 | 0 | 1 | 0 | 1.93 | .282 | 1.13 | 4.0 | 6.5 | 12.0 | 18.2 | 8 | 5 | 4 | 0 | 13 | 24 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 2.67 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 13 | 0 | 1 | 2 | 2.25 | .321 | 1.33 | 6.8 | 5.3 | 9.8 | 12.0 | 9 | 3 | 3 | 1 | 7 | 13 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.92 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 17 | 0 | 1 | 0 | 3.92 | .271 | 1.06 | 6.8 | 3.2 | 7.2 | 20.2 | 15 | 9 | 9 | 2 | 7 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.90 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |