| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 24 | 24 | 8 | 13 | 4.19 | .318 | 1.36 | 8.6 | 3.8 | 7.9 | 184.2 | 175 | 98 | 86 | 20 | 77 | 161 | 7 | 0 | 0 | 1 | 14 | 6 | 4 | 4.02 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 23 | 23 | 9 | 12 | 4.05 | .313 | 1.34 | 8.6 | 3.6 | 8.5 | 157.2 | 150 | 74 | 71 | 13 | 62 | 149 | 2 | 0 | 0 | 0 | 11 | 3 | 1 | 3.42 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 23 | 23 | 9 | 11 | 4.80 | .331 | 1.46 | 9.8 | 3.3 | 4.4 | 159.1 | 174 | 98 | 85 | 17 | 58 | 78 | 4 | 0 | 0 | 2 | 11 | 4 | 9 | 4.58 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 71 | 22 | 22 | 10 | 12 | 4.95 | .334 | 1.50 | 10.7 | 2.8 | 7.7 | 160.0 | 191 | 93 | 88 | 33 | 49 | 136 | 8 | 0 | 0 | 0 | 10 | 1 | 2 | 4.92 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 22 | 22 | 3 | 12 | 6.91 | .366 | 1.71 | 11.5 | 3.9 | 7.6 | 142.0 | 182 | 117 | 109 | 28 | 61 | 120 | 2 | 0 | 0 | 0 | 5 | 3 | 4 | 5.23 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 63 | 0 | 4 | 0 | 2.90 | .286 | 1.18 | 7.3 | 3.4 | 10.0 | 80.2 | 65 | 27 | 26 | 12 | 30 | 89 | 0 | 8 | 5 | 0 | 0 | 2 | 0 | 3.93 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 37 | 0 | 3 | 1 | 2.53 | .224 | 0.84 | 4.5 | 3.2 | 11.4 | 42.2 | 21 | 12 | 12 | 0 | 15 | 53 | 0 | 6 | 1 | 0 | 0 | 1 | 2 | 1.62 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 23 | 0 | 1 | 3 | 3.00 | .287 | 1.21 | 8.6 | 2.3 | 6.8 | 24.0 | 23 | 9 | 8 | 1 | 6 | 18 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.79 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 16 | 0 | 0 | 1 | 4.96 | .402 | 2.02 | 10.7 | 7.9 | 7.3 | 16.1 | 19 | 10 | 9 | 1 | 14 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.81 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 22 | 0 | 0 | 0 | 6.04 | .356 | 1.66 | 11.5 | 3.7 | 5.3 | 22.1 | 28 | 15 | 15 | 4 | 9 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.41 |