| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 74 | 7 | 7 | 2 | 2 | 4.70 | .281 | 1.17 | 7.2 | 3.6 | 6.9 | 30.2 | 24 | 16 | 16 | 3 | 12 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.97 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 68 | 7 | 7 | 1 | 3 | 10.67 | .423 | 2.16 | 15.4 | 4.5 | 6.4 | 28.2 | 48 | 34 | 34 | 11 | 14 | 20 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 8.29 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 8 | 7 | 3 | 4 | 4.23 | .340 | 1.54 | 10.4 | 3.7 | 7.6 | 44.2 | 51 | 24 | 21 | 7 | 18 | 37 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.61 |
| CL | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 91 | 15 | 0 | 1 | 1 | 3.29 | .317 | 1.39 | 9.7 | 3.5 | 8.3 | 13.2 | 14 | 5 | 5 | 0 | 5 | 12 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 2.31 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 85 | 19 | 0 | 1 | 0 | 2.96 | .293 | 1.24 | 7.7 | 3.7 | 7.7 | 27.1 | 23 | 10 | 9 | 1 | 11 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.00 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 15 | 0 | 3 | 0 | 2.70 | .213 | 0.81 | 5.5 | 2.0 | 10.6 | 23.1 | 14 | 7 | 7 | 3 | 5 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 64 | 11 | 0 | 0 | 2 | 5.65 | .386 | 1.81 | 12.9 | 3.9 | 7.1 | 14.1 | 20 | 10 | 9 | 2 | 6 | 11 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.79 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 10 | 0 | 0 | 1 | 6.92 | .278 | 1.15 | 6.2 | 4.2 | 9.0 | 13.0 | 9 | 10 | 10 | 2 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.38 |