| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 15 | 15 | 8 | 4 | 4.53 | .327 | 1.43 | 8.7 | 4.2 | 6.6 | 101.1 | 98 | 56 | 51 | 14 | 47 | 74 | 3 | 0 | 0 | 1 | 7 | 3 | 2 | 4.82 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 15 | 15 | 5 | 5 | 4.91 | .322 | 1.40 | 8.8 | 3.8 | 7.1 | 95.1 | 93 | 55 | 52 | 21 | 40 | 75 | 1 | 0 | 0 | 0 | 5 | 3 | 0 | 5.65 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 70 | 15 | 15 | 8 | 5 | 3.08 | .276 | 1.13 | 7.2 | 3.0 | 6.2 | 96.1 | 77 | 37 | 33 | 10 | 32 | 66 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.01 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 51 | 15 | 15 | 1 | 9 | 10.46 | .447 | 2.35 | 16.1 | 5.0 | 7.1 | 68.0 | 122 | 87 | 79 | 17 | 38 | 54 | 0 | 0 | 0 | 0 | 1 | 5 | 2 | 6.56 |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2008 | R | 38 | 15 | 15 | 5 | 5 | 5.48 | .343 | 1.55 | 10.5 | 3.5 | 6.3 | 88.2 | 103 | 56 | 54 | 18 | 34 | 62 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 5.48 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 38 | 0 | 3 | 2 | 3.89 | .294 | 1.23 | 8.0 | 3.1 | 9.6 | 44.0 | 39 | 19 | 19 | 6 | 15 | 47 | 0 | 5 | 2 | 0 | 0 | 1 | 2 | 3.73 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 51 | 33 | 0 | 1 | 2 | 6.52 | .341 | 1.53 | 9.2 | 4.7 | 7.6 | 38.2 | 39 | 28 | 28 | 9 | 20 | 32 | 0 | 1 | 3 | 0 | 0 | 1 | 3 | 6.05 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 36 | 28 | 0 | 2 | 1 | 4.08 | .323 | 1.43 | 8.7 | 4.5 | 10.3 | 28.2 | 27 | 13 | 13 | 4 | 14 | 32 | 0 | 5 | 0 | 0 | 0 | 0 | 2 | 4.07 |
| RP | Cordero, F.Cordero, Francisco >> | 32 | 2007 | R | 25 | 28 | 0 | 0 | 0 | 9.10 | .407 | 1.99 | 11.8 | 6.5 | 8.7 | 29.2 | 38 | 30 | 30 | 6 | 21 | 28 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 6.14 |
| SP | Miller, W.Miller, Wade >> | 25 | 2001 | R | 27 | 8 | 0 | 1 | 2 | 10.64 | .431 | 2.27 | 13.1 | 7.4 | 4.9 | 11.0 | 16 | 13 | 13 | 4 | 9 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.09 |