| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 16 | 16 | 8 | 5 | 3.19 | .286 | 1.17 | 6.0 | 4.6 | 9.8 | 101.2 | 67 | 37 | 36 | 10 | 52 | 110 | 1 | 0 | 0 | 1 | 10 | 3 | 2 | 3.74 |
| SP | Perez, O.Perez, Oliver # >> | 23 | 2004 | L | 75 | 15 | 15 | 6 | 4 | 4.25 | .286 | 1.18 | 7.3 | 3.4 | 8.9 | 101.2 | 82 | 48 | 48 | 15 | 38 | 100 | 1 | 0 | 0 | 1 | 8 | 2 | 2 | 4.14 |
| SP | Burnett, A.Burnett, A.J. >> | 25 | 2002 | R | 56 | 15 | 15 | 6 | 7 | 4.30 | .337 | 1.48 | 8.2 | 5.2 | 7.6 | 98.1 | 89 | 61 | 47 | 14 | 57 | 83 | 1 | 0 | 0 | 0 | 7 | 4 | 2 | 5.03 |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 43 | 15 | 15 | 6 | 6 | 5.99 | .339 | 1.54 | 10.8 | 3.2 | 10.3 | 82.2 | 98 | 55 | 55 | 16 | 29 | 94 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 4.30 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 41 | 0 | 3 | 1 | 4.07 | .321 | 1.36 | 9.4 | 3.0 | 9.4 | 48.2 | 50 | 22 | 22 | 8 | 16 | 50 | 0 | 7 | 4 | 0 | 0 | 3 | 6 | 4.27 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 54 | 37 | 0 | 3 | 1 | 4.09 | .286 | 1.18 | 8.0 | 2.7 | 9.4 | 44.0 | 39 | 20 | 20 | 4 | 13 | 46 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.05 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 41 | 25 | 0 | 1 | 1 | 3.31 | .279 | 1.10 | 6.8 | 3.4 | 11.8 | 32.2 | 24 | 12 | 12 | 2 | 12 | 42 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 2.50 |
| SP | Washburn, J.Washburn, Jarrod >> | 28 | 2002 | L | 32 | 13 | 0 | 1 | 2 | 4.86 | .296 | 1.26 | 9.0 | 2.8 | 5.6 | 16.2 | 16 | 9 | 9 | 2 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.31 |