| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 99 | 16 | 16 | 6 | 5 | 4.01 | .301 | 1.27 | 9.7 | 1.7 | 8.9 | 114.1 | 123 | 53 | 51 | 13 | 22 | 113 | 3 | 0 | 0 | 1 | 9 | 3 | 2 | 3.16 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 82 | 16 | 16 | 5 | 5 | 4.77 | .303 | 1.28 | 9.3 | 2.4 | 8.8 | 103.2 | 106 | 55 | 55 | 15 | 27 | 101 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 3.78 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 68 | 16 | 16 | 2 | 12 | 7.02 | .359 | 1.64 | 11.9 | 2.9 | 6.3 | 101.1 | 134 | 89 | 79 | 22 | 32 | 71 | 2 | 0 | 0 | 1 | 3 | 4 | 2 | 5.50 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 15 | 15 | 7 | 6 | 4.78 | .291 | 1.21 | 7.8 | 3.1 | 7.1 | 105.1 | 91 | 59 | 56 | 18 | 36 | 83 | 1 | 0 | 0 | 0 | 7 | 3 | 1 | 4.76 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 55 | 15 | 15 | 7 | 6 | 4.71 | .318 | 1.37 | 9.5 | 3.0 | 8.0 | 91.2 | 96 | 50 | 48 | 14 | 30 | 81 | 0 | 0 | 0 | 0 | 8 | 2 | 3 | 4.27 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 42 | 0 | 3 | 3 | 2.96 | .286 | 1.16 | 8.3 | 2.3 | 8.3 | 51.2 | 47 | 23 | 17 | 10 | 13 | 47 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 4.59 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 46 | 12 | 0 | 0 | 2 | 2.57 | .250 | 1.00 | 7.1 | 1.9 | 7.1 | 14.0 | 11 | 4 | 4 | 2 | 3 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.93 |
| RP | Kim, B.Kim, Byung-Hyun >> | 23 | 2002 | R | 37 | 15 | 0 | 1 | 0 | 4.34 | .341 | 1.45 | 11.0 | 2.5 | 8.0 | 18.2 | 22 | 9 | 9 | 2 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.83 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 47 | 3 | 0 | 0 | 0 | 0.00 | .400 | 2.00 | 15.8 | 2.3 | 2.3 | 4.0 | 7 | 4 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.25 |