| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 99 | 15 | 15 | 6 | 6 | 3.47 | .278 | 1.14 | 8.0 | 2.3 | 8.0 | 103.2 | 92 | 43 | 40 | 10 | 26 | 91 | 2 | 0 | 0 | 0 | 9 | 2 | 3 | 3.31 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 15 | 15 | 5 | 2 | 3.69 | .300 | 1.28 | 8.1 | 3.5 | 6.8 | 92.2 | 83 | 38 | 38 | 14 | 36 | 69 | 0 | 0 | 0 | 0 | 7 | 0 | 2 | 4.65 |
| SP | Hudson, T.Hudson, Tim # >> | 28 | 2003 | R | 74 | 15 | 15 | 6 | 2 | 5.42 | .335 | 1.46 | 10.0 | 3.1 | 5.2 | 78.0 | 87 | 49 | 47 | 11 | 27 | 45 | 1 | 0 | 0 | 0 | 6 | 4 | 2 | 4.87 |
| SP | Garcia, F.Garcia, Freddy >> | 26 | 2001 | R | 61 | 16 | 15 | 3 | 7 | 5.00 | .308 | 1.29 | 8.6 | 3.1 | 6.1 | 84.2 | 80 | 47 | 47 | 16 | 29 | 57 | 2 | 1 | 0 | 0 | 7 | 4 | 2 | 5.30 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 53 | 15 | 15 | 0 | 9 | 7.56 | .370 | 1.72 | 11.8 | 3.9 | 8.0 | 72.2 | 94 | 63 | 61 | 15 | 31 | 64 | 1 | 0 | 0 | 0 | 3 | 3 | 6 | 5.35 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 40 | 0 | 5 | 2 | 3.98 | .254 | 1.00 | 5.9 | 3.1 | 8.0 | 52.0 | 34 | 23 | 23 | 5 | 18 | 46 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 3.58 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 33 | 0 | 2 | 0 | 3.25 | .236 | 0.90 | 6.3 | 1.8 | 7.4 | 44.1 | 31 | 16 | 16 | 3 | 9 | 36 | 0 | 0 | 3 | 0 | 0 | 1 | 4 | 2.93 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 78 | 26 | 0 | 5 | 2 | 3.68 | .393 | 1.91 | 9.9 | 7.4 | 8.1 | 29.1 | 32 | 12 | 12 | 2 | 24 | 26 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.69 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 66 | 25 | 0 | 0 | 1 | 6.49 | .352 | 1.59 | 10.4 | 4.2 | 6.6 | 26.1 | 30 | 19 | 19 | 4 | 12 | 19 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 5.04 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 31 | 0 | 1 | 6 | 3.86 | .331 | 1.45 | 9.6 | 3.6 | 9.6 | 30.1 | 32 | 13 | 13 | 0 | 12 | 32 | 0 | 16 | 0 | 0 | 0 | 1 | 2 | 2.17 |