| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 99 | 5 | 5 | 1 | 1 | 4.80 | .343 | 1.50 | 10.2 | 3.3 | 7.8 | 30.0 | 34 | 16 | 16 | 2 | 11 | 26 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 3.43 |
| SP | Blanton, J.Blanton, Joe >> | 28 | 2008 | R | 46 | 2 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 4.5 | 2.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Romero, J.Romero, J.C. >> | 32 | 2008 | L | 75 | 9 | 0 | 2 | 0 | 0.82 | .327 | 1.45 | 6.5 | 6.5 | 4.1 | 11.0 | 8 | 1 | 1 | 0 | 8 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.27 |
| RP | Madson, R.Madson, Ryan >> | 28 | 2008 | R | 69 | 9 | 0 | 1 | 1 | 5.25 | .333 | 1.50 | 11.3 | 2.3 | 6.8 | 12.0 | 15 | 7 | 7 | 3 | 3 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.50 |
| RP | Durbin, C.Durbin, Chad >> | 31 | 2008 | R | 60 | 8 | 0 | 1 | 0 | 7.20 | .333 | 1.50 | 9.0 | 4.5 | 6.3 | 10.0 | 10 | 8 | 8 | 1 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.40 |
| RP | Seanez, R.Seanez, Rudy >> | 40 | 2008 | R | 49 | 7 | 0 | 0 | 0 | 7.88 | .429 | 2.00 | 16.9 | 1.1 | 4.5 | 8.0 | 15 | 7 | 7 | 2 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 6.38 |