| SP | Hamels, C.Hamels, Cole >> | 30 | 2012 | L | 93 | 41 | 41 | 12 | 17 | 3.55 | .291 | 1.20 | 8.4 | 2.4 | 8.9 | 281.1 | 263 | 116 | 111 | 19 | 75 | 277 | 5 | 0 | 0 | 2 | 29 | 8 | 5 | 2.79 |
| SP | Halladay, R.Halladay, Roy >> | 36 | 2012 | R | 65 | 40 | 40 | 9 | 10 | 4.32 | .321 | 1.40 | 9.6 | 3.0 | 7.5 | 250.0 | 266 | 123 | 120 | 29 | 84 | 207 | 1 | 0 | 0 | 0 | 23 | 5 | 5 | 3.92 |
| SP | Blanton, J.Blanton, Joe >> | 33 | 2012 | R | 50 | 40 | 40 | 17 | 11 | 3.90 | .323 | 1.39 | 10.0 | 2.5 | 7.6 | 251.2 | 280 | 113 | 109 | 23 | 71 | 213 | 0 | 0 | 0 | 0 | 24 | 10 | 5 | 3.46 |
| RP | Valdes, R.Valdes, Raul >> | 35 | 2012 | L | 98 | 89 | 0 | 6 | 2 | 2.89 | .240 | 0.92 | 5.7 | 2.7 | 9.3 | 71.2 | 45 | 23 | 23 | 7 | 21 | 73 | 0 | 0 | 5 | 0 | 0 | 2 | 0 | 3.20 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 33 | 2012 | R | 87 | 92 | 0 | 3 | 3 | 3.65 | .281 | 1.17 | 7.4 | 3.3 | 11.2 | 66.2 | 54 | 27 | 27 | 6 | 24 | 82 | 0 | 2 | 6 | 0 | 0 | 0 | 0 | 2.79 |
| RP | Bastardo, A.Bastardo, Antonio >> | 28 | 2012 | L | 89 | 64 | 0 | 3 | 2 | 2.25 | .250 | 1.00 | 6.8 | 2.3 | 13.2 | 28.0 | 21 | 7 | 7 | 2 | 7 | 41 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 1.75 |
| RP | Rosenberg, B.Rosenberg, B.J. >> | 27 | 2012 | R | 80 | 61 | 0 | 1 | 2 | 2.60 | .254 | 0.98 | 5.5 | 3.3 | 6.2 | 52.0 | 32 | 15 | 15 | 3 | 19 | 36 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 3.58 |
| RP | Lindblom, J.Lindblom, Josh >> | 26 | 2012 | R | 77 | 33 | 0 | 9 | 4 | 2.48 | .298 | 1.21 | 7.1 | 3.7 | 8.7 | 29.0 | 23 | 8 | 8 | 1 | 12 | 28 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 2.97 |
| RP | Kendrick, K.Kendrick, Kyle >> | 29 | 2012 | R | 44 | 32 | 0 | 1 | 3 | 3.43 | .292 | 1.21 | 8.4 | 2.6 | 6.2 | 42.0 | 39 | 18 | 16 | 3 | 12 | 29 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 3.48 |
| CL | Horst, J.Horst, Jeremy >> | 27 | 2012 | L | 96 | 56 | 0 | 5 | 10 | 3.66 | .324 | 1.39 | 7.9 | 4.6 | 12.1 | 64.0 | 56 | 28 | 26 | 6 | 33 | 86 | 0 | 24 | 6 | 0 | 0 | 3 | 1 | 3.22 |
| RP | Stutes, M.Stutes, Michael >> | 24 | 2011 | R | 73 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Madson, R.Madson, Ryan >> | 31 | 2011 | R | 73 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Herndon, D.Herndon, David >> | 25 | 2011 | R | 40 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |