| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 30 | 30 | 14 | 8 | 3.32 | .284 | 1.18 | 7.3 | 3.4 | 8.7 | 211.2 | 170 | 83 | 78 | 18 | 80 | 204 | 2 | 0 | 0 | 1 | 20 | 2 | 2 | 3.34 |
| SP | Gibson, B.Gibson, Bob † >> | 33 | 1968 | R | 93 | 30 | 30 | 18 | 9 | 3.08 | .269 | 1.10 | 7.4 | 2.4 | 6.2 | 248.0 | 205 | 93 | 85 | 29 | 67 | 171 | 16 | 0 | 0 | 4 | 20 | 2 | 2 | 3.98 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 29 | 29 | 17 | 6 | 3.90 | .290 | 1.18 | 7.8 | 2.8 | 4.4 | 216.2 | 188 | 95 | 94 | 22 | 68 | 105 | 7 | 0 | 0 | 2 | 15 | 9 | 5 | 4.42 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 73 | 0 | 6 | 6 | 3.25 | .335 | 1.47 | 7.7 | 5.7 | 9.7 | 74.2 | 63 | 29 | 27 | 7 | 47 | 80 | 0 | 11 | 6 | 0 | 0 | 3 | 3 | 4.09 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 47 | 0 | 5 | 4 | 3.80 | .300 | 1.27 | 5.6 | 5.9 | 8.2 | 47.1 | 29 | 21 | 20 | 7 | 31 | 43 | 0 | 6 | 6 | 0 | 0 | 1 | 2 | 5.15 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 23 | 0 | 2 | 2 | 6.75 | .413 | 2.06 | 11.6 | 7.3 | 6.9 | 21.1 | 27 | 16 | 16 | 3 | 17 | 16 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.90 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 21 | 0 | 2 | 2 | 4.67 | .289 | 1.19 | 8.0 | 2.7 | 7.3 | 27.0 | 24 | 15 | 14 | 7 | 8 | 22 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.74 |