| SP | Glasnow, T.Glasnow, Tyler † >> | 29 | 2023 | R | 97 | 27 | 27 | 14 | 7 | 4.26 | .316 | 1.36 | 9.0 | 3.2 | 10.2 | 156.1 | 156 | 77 | 74 | 16 | 56 | 177 | 0 | 0 | 0 | 0 | 13 | 5 | 3 | 3.24 |
| SP | Scherzer, M.Scherzer, Max >> | 39 | 2023 | R | 89 | 26 | 26 | 8 | 7 | 5.24 | .312 | 1.32 | 9.3 | 2.6 | 10.6 | 137.1 | 141 | 81 | 80 | 27 | 40 | 162 | 1 | 0 | 0 | 0 | 11 | 6 | 1 | 4.20 |
| SP | Snell, B.Snell, Blake † >> | 30 | 2023 | L | 81 | 26 | 26 | 16 | 1 | 3.29 | .300 | 1.24 | 6.7 | 4.5 | 10.8 | 150.2 | 112 | 57 | 55 | 16 | 75 | 180 | 0 | 0 | 0 | 0 | 13 | 7 | 5 | 3.63 |
| SP | Maeda, K.Maeda, Kenta † >> | 35 | 2023 | R | 70 | 26 | 26 | 9 | 5 | 4.27 | .315 | 1.35 | 8.7 | 3.5 | 10.5 | 130.2 | 126 | 63 | 62 | 23 | 51 | 151 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 4.22 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 100 | 68 | 0 | 3 | 2 | 2.79 | .265 | 1.05 | 5.2 | 4.2 | 12.2 | 100.0 | 58 | 31 | 31 | 8 | 47 | 135 | 0 | 2 | 1 | 0 | 0 | 3 | 8 | 2.84 |
| RP | Thielbar, C.Thielbar, Caleb >> | 36 | 2023 | L | 87 | 63 | 0 | 4 | 3 | 3.63 | .259 | 1.03 | 7.4 | 1.9 | 10.8 | 94.1 | 77 | 39 | 38 | 11 | 20 | 113 | 0 | 4 | 1 | 0 | 0 | 2 | 3 | 2.82 |
| RP | Pressly, R.Pressly, Ryan >> | 34 | 2023 | R | 73 | 62 | 0 | 3 | 3 | 4.61 | .339 | 1.45 | 10.6 | 2.5 | 10.7 | 68.1 | 80 | 37 | 35 | 12 | 19 | 81 | 0 | 9 | 6 | 0 | 0 | 6 | 3 | 4.01 |
| RP | Coulombe, D.Coulombe, Daniel >> | 33 | 2023 | L | 66 | 57 | 0 | 3 | 2 | 3.48 | .262 | 1.01 | 7.3 | 1.9 | 10.9 | 72.1 | 58 | 29 | 28 | 11 | 15 | 87 | 0 | 6 | 1 | 0 | 0 | 4 | 1 | 3.36 |
| SP | Heaney, A.Heaney, Andrew >> | 32 | 2023 | L | 34 | 31 | 0 | 9 | 5 | 3.42 | .325 | 1.42 | 8.1 | 4.8 | 11.1 | 52.2 | 47 | 21 | 20 | 6 | 28 | 64 | 0 | 6 | 1 | 0 | 0 | 1 | 1 | 3.71 |