| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 14 | 14 | 7 | 5 | 3.02 | .236 | 0.92 | 6.2 | 2.1 | 10.1 | 98.1 | 67 | 34 | 33 | 15 | 23 | 110 | 1 | 0 | 0 | 0 | 10 | 1 | 0 | 3.48 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 88 | 13 | 13 | 6 | 3 | 4.40 | .296 | 1.25 | 8.5 | 2.8 | 8.4 | 73.2 | 69 | 36 | 36 | 10 | 23 | 68 | 0 | 0 | 0 | 0 | 6 | 1 | 5 | 3.90 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 12 | 12 | 8 | 2 | 2.49 | .272 | 1.11 | 6.4 | 3.6 | 10.7 | 76.0 | 54 | 21 | 21 | 6 | 30 | 90 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 2.88 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 78 | 13 | 13 | 7 | 2 | 3.80 | .316 | 1.39 | 8.9 | 3.6 | 6.3 | 83.0 | 82 | 36 | 35 | 11 | 33 | 58 | 2 | 0 | 0 | 1 | 7 | 0 | 0 | 4.52 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 26 | 0 | 6 | 0 | 0.95 | .274 | 1.13 | 5.8 | 4.5 | 10.3 | 28.1 | 18 | 5 | 3 | 3 | 14 | 32 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.61 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 71 | 19 | 0 | 0 | 1 | 3.63 | .257 | 0.98 | 6.9 | 2.1 | 11.1 | 17.1 | 13 | 8 | 7 | 1 | 4 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.18 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 56 | 15 | 0 | 0 | 0 | 7.24 | .431 | 2.20 | 10.4 | 10.4 | 10.4 | 13.2 | 15 | 12 | 11 | 0 | 15 | 15 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.38 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 5 | 1 | 0 | 1 | 3.44 | .257 | 1.04 | 8.0 | 1.5 | 10.5 | 18.1 | 16 | 7 | 7 | 5 | 3 | 21 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 4.78 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 34 | 0 | 3 | 1 | 4.41 | .278 | 1.13 | 9.0 | 1.3 | 8.7 | 34.2 | 34 | 17 | 17 | 4 | 5 | 33 | 0 | 22 | 2 | 0 | 0 | 1 | 0 | 3.12 |
| SU | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 27 | 0 | 1 | 0 | 3.62 | .305 | 1.28 | 7.0 | 4.7 | 9.7 | 27.1 | 21 | 11 | 11 | 3 | 14 | 29 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 3.96 |