| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 37 | 37 | 19 | 5 | 2.72 | .253 | 0.98 | 6.7 | 2.2 | 11.1 | 231.2 | 172 | 71 | 70 | 28 | 56 | 285 | 0 | 0 | 0 | 0 | 26 | 7 | 0 | 2.93 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 35 | 35 | 11 | 9 | 4.46 | .277 | 1.11 | 7.0 | 3.0 | 8.7 | 197.2 | 154 | 98 | 98 | 38 | 66 | 191 | 0 | 0 | 0 | 0 | 18 | 7 | 8 | 4.68 |
| SP | Fernandez, J.Fernandez, Jose † >> | 21 | 2013 | R | 83 | 33 | 33 | 22 | 5 | 2.22 | .255 | 1.01 | 5.7 | 3.4 | 8.7 | 227.0 | 143 | 56 | 56 | 19 | 87 | 220 | 2 | 0 | 0 | 1 | 28 | 3 | 3 | 3.34 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 68 | 31 | 30 | 14 | 3 | 3.01 | .274 | 1.10 | 7.0 | 3.0 | 8.6 | 185.2 | 143 | 70 | 62 | 21 | 62 | 177 | 2 | 0 | 0 | 2 | 21 | 5 | 1 | 3.65 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 71 | 49 | 0 | 4 | 0 | 2.89 | .260 | 1.04 | 5.4 | 3.9 | 9.8 | 53.0 | 32 | 18 | 17 | 3 | 23 | 58 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.91 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 47 | 0 | 6 | 0 | 1.92 | .239 | 0.91 | 4.2 | 4.0 | 10.0 | 56.1 | 26 | 12 | 12 | 1 | 25 | 62 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 2.46 |
| SU | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 77 | 0 | 6 | 6 | 3.81 | .271 | 1.10 | 7.7 | 2.3 | 8.9 | 82.2 | 70 | 35 | 35 | 15 | 21 | 81 | 0 | 6 | 6 | 0 | 0 | 1 | 3 | 4.21 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 81 | 0 | 9 | 2 | 1.24 | .213 | 0.81 | 4.2 | 3.1 | 8.4 | 87.1 | 41 | 12 | 12 | 4 | 30 | 81 | 0 | 51 | 2 | 0 | 0 | 0 | 1 | 2.77 |