| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 36 | 36 | 14 | 13 | 3.79 | .304 | 1.29 | 7.7 | 4.0 | 9.7 | 246.2 | 210 | 105 | 104 | 30 | 108 | 265 | 1 | 0 | 0 | 0 | 23 | 5 | 6 | 3.81 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 91 | 35 | 35 | 16 | 10 | 4.87 | .298 | 1.26 | 8.5 | 2.8 | 9.7 | 236.1 | 224 | 132 | 128 | 43 | 73 | 255 | 3 | 0 | 0 | 2 | 17 | 4 | 6 | 4.19 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 33 | 33 | 3 | 16 | 6.06 | .361 | 1.66 | 9.3 | 5.7 | 9.9 | 139.2 | 144 | 98 | 94 | 28 | 88 | 153 | 0 | 0 | 0 | 0 | 0 | 5 | 5 | 5.42 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 65 | 31 | 31 | 12 | 12 | 4.96 | .320 | 1.40 | 9.0 | 3.6 | 6.6 | 223.1 | 222 | 126 | 123 | 30 | 90 | 164 | 3 | 0 | 0 | 1 | 12 | 3 | 0 | 4.53 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 62 | 0 | 3 | 5 | 3.58 | .300 | 1.27 | 7.3 | 4.2 | 11.2 | 73.0 | 59 | 29 | 29 | 12 | 34 | 91 | 0 | 5 | 3 | 0 | 0 | 1 | 3 | 4.08 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 53 | 0 | 7 | 3 | 3.79 | .293 | 1.23 | 6.7 | 4.5 | 10.0 | 54.2 | 40 | 24 | 23 | 10 | 27 | 60 | 0 | 6 | 2 | 0 | 0 | 1 | 4 | 4.74 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 41 | 0 | 3 | 1 | 2.91 | .319 | 1.40 | 8.6 | 4.1 | 7.6 | 46.1 | 44 | 15 | 15 | 4 | 21 | 39 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.80 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 57 | 5 | 0 | 1 | 0 | 1.13 | .111 | 0.38 | 2.3 | 1.1 | 7.9 | 8.0 | 2 | 1 | 1 | 1 | 1 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.25 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 65 | 37 | 0 | 0 | 4 | 5.83 | .365 | 1.67 | 10.8 | 4.2 | 9.5 | 54.0 | 65 | 36 | 35 | 12 | 25 | 57 | 0 | 2 | 1 | 0 | 0 | 3 | 4 | 5.33 |