| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 11 | 11 | 3 | 5 | 2.58 | .263 | 1.03 | 6.0 | 3.4 | 10.1 | 80.1 | 53 | 23 | 23 | 9 | 30 | 90 | 1 | 0 | 0 | 0 | 10 | 3 | 2 | 3.45 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 11 | 11 | 3 | 5 | 6.12 | .347 | 1.55 | 10.5 | 3.6 | 10.1 | 67.2 | 78 | 48 | 46 | 17 | 27 | 75 | 0 | 0 | 0 | 0 | 4 | 3 | 2 | 5.40 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 10 | 10 | 0 | 5 | 6.65 | .350 | 1.62 | 9.2 | 5.4 | 10.7 | 43.1 | 44 | 32 | 32 | 14 | 26 | 51 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 6.67 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 10 | 10 | 5 | 5 | 3.97 | .280 | 1.14 | 7.7 | 2.6 | 6.2 | 77.0 | 66 | 36 | 34 | 8 | 22 | 53 | 3 | 0 | 0 | 1 | 5 | 2 | 0 | 3.91 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 80 | 20 | 0 | 1 | 1 | 1.99 | .333 | 1.50 | 9.8 | 4.1 | 13.5 | 22.2 | 24 | 5 | 5 | 2 | 10 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2.55 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 16 | 0 | 3 | 1 | 4.96 | .319 | 1.35 | 8.4 | 3.9 | 7.3 | 16.1 | 15 | 9 | 9 | 2 | 7 | 13 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.50 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 11 | 0 | 1 | 1 | 9.00 | .460 | 2.56 | 17.0 | 6.0 | 8.0 | 9.0 | 17 | 9 | 9 | 2 | 6 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.11 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 59 | 2 | 0 | 1 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 9.0 | 2.2 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 64 | 7 | 0 | 0 | 0 | 2.92 | .260 | 1.05 | 7.5 | 2.3 | 12.8 | 12.1 | 10 | 4 | 4 | 2 | 3 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.08 |