| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 14 | 14 | 6 | 6 | 4.28 | .290 | 1.21 | 8.6 | 2.3 | 9.7 | 101.0 | 96 | 52 | 48 | 15 | 26 | 109 | 4 | 0 | 0 | 1 | 7 | 2 | 2 | 3.60 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 14 | 14 | 7 | 4 | 4.29 | .316 | 1.36 | 9.0 | 3.3 | 10.0 | 94.1 | 94 | 45 | 45 | 15 | 34 | 104 | 2 | 0 | 0 | 1 | 7 | 3 | 1 | 4.04 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 13 | 13 | 4 | 7 | 5.54 | .326 | 1.44 | 9.1 | 3.8 | 6.9 | 78.0 | 79 | 51 | 48 | 15 | 33 | 60 | 0 | 0 | 0 | 0 | 6 | 1 | 2 | 5.27 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 64 | 15 | 13 | 3 | 8 | 6.11 | .362 | 1.65 | 10.7 | 4.2 | 5.1 | 81.0 | 96 | 58 | 55 | 15 | 38 | 46 | 2 | 0 | 0 | 0 | 4 | 4 | 0 | 5.83 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 38 | 0 | 1 | 2 | 2.98 | .272 | 1.09 | 8.2 | 1.7 | 10.2 | 54.1 | 49 | 18 | 18 | 5 | 10 | 61 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 2.61 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 90 | 28 | 0 | 2 | 0 | 4.50 | .282 | 1.18 | 7.4 | 3.2 | 9.5 | 34.0 | 28 | 19 | 17 | 8 | 12 | 36 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 25 | 0 | 2 | 0 | 3.00 | .302 | 1.30 | 7.0 | 4.7 | 12.0 | 27.0 | 21 | 10 | 9 | 3 | 14 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.33 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 19 | 0 | 2 | 1 | 1.17 | .216 | 0.83 | 3.9 | 3.5 | 8.6 | 23.0 | 10 | 3 | 3 | 2 | 9 | 22 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.39 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 19 | 0 | 0 | 1 | 2.01 | .256 | 1.03 | 6.1 | 3.3 | 7.8 | 22.1 | 15 | 5 | 5 | 3 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.14 |