| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 13 | 13 | 8 | 3 | 2.36 | .279 | 1.11 | 6.6 | 3.4 | 10.4 | 91.1 | 67 | 38 | 24 | 11 | 34 | 105 | 1 | 0 | 0 | 1 | 10 | 5 | 2 | 3.55 |
| SP | Flaherty, J.Flaherty, Jack # >> | 23 | 2019 | R | 83 | 13 | 13 | 3 | 6 | 4.63 | .300 | 1.27 | 8.0 | 3.5 | 9.0 | 70.0 | 62 | 48 | 36 | 11 | 27 | 70 | 1 | 0 | 0 | 0 | 7 | 1 | 2 | 4.24 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 71 | 13 | 12 | 1 | 7 | 7.76 | .389 | 1.91 | 12.9 | 4.4 | 6.6 | 60.1 | 86 | 61 | 52 | 10 | 29 | 44 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 5.15 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 13 | 12 | 3 | 4 | 5.23 | .317 | 1.39 | 10.1 | 2.6 | 9.5 | 51.2 | 57 | 34 | 30 | 8 | 15 | 54 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 3.80 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 41 | 0 | 2 | 2 | 2.31 | .280 | 1.15 | 6.4 | 4.0 | 9.8 | 58.1 | 41 | 19 | 15 | 1 | 26 | 63 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 2.45 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 40 | 0 | 1 | 1 | 4.25 | .296 | 1.25 | 7.3 | 3.9 | 8.7 | 53.0 | 43 | 27 | 25 | 7 | 23 | 51 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.15 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 37 | 0 | 2 | 4 | 3.94 | .297 | 1.23 | 8.6 | 2.6 | 10.0 | 45.2 | 43 | 22 | 20 | 5 | 13 | 50 | 0 | 6 | 4 | 0 | 0 | 2 | 0 | 3.22 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 26 | 0 | 3 | 1 | 2.04 | .312 | 1.36 | 6.7 | 5.7 | 11.3 | 35.1 | 26 | 9 | 8 | 5 | 22 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.23 |