| SP | Johnson, R.Johnson, Randy # >> | 39 | 2002 | L | 64 | 32 | 32 | 12 | 14 | 4.20 | .311 | 1.34 | 9.2 | 2.9 | 9.0 | 207.2 | 211 | 104 | 97 | 26 | 67 | 207 | 3 | 0 | 0 | 0 | 19 | 3 | 4 | 3.65 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 85 | 32 | 32 | 7 | 16 | 4.64 | .322 | 1.43 | 9.1 | 3.7 | 9.0 | 184.1 | 187 | 99 | 95 | 34 | 76 | 184 | 1 | 0 | 0 | 0 | 14 | 0 | 6 | 4.64 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 69 | 32 | 32 | 12 | 12 | 3.44 | .297 | 1.23 | 7.1 | 4.0 | 9.2 | 201.2 | 159 | 78 | 77 | 22 | 90 | 206 | 1 | 0 | 0 | 1 | 18 | 6 | 0 | 3.81 |
| SP | Higuera, T.Higuera, Teddy >> | 28 | 1986 | L | 3 | 31 | 31 | 9 | 13 | 6.30 | .359 | 1.63 | 10.7 | 3.9 | 5.5 | 183.0 | 218 | 139 | 128 | 27 | 80 | 111 | 1 | 0 | 0 | 0 | 8 | 9 | 3 | 5.16 |
| CL | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 51 | 0 | 1 | 4 | 3.48 | .289 | 1.22 | 7.1 | 4.1 | 5.5 | 51.2 | 40 | 20 | 20 | 9 | 23 | 31 | 0 | 20 | 6 | 0 | 0 | 0 | 0 | 5.43 |
| SU | Feliz, N.Feliz, Neftali # >> | 21 | 2009 | R | 97 | 52 | 0 | 0 | 7 | 5.76 | .322 | 1.43 | 7.7 | 5.3 | 9.2 | 54.2 | 46 | 37 | 35 | 7 | 32 | 55 | 0 | 14 | 11 | 0 | 0 | 0 | 0 | 4.43 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 77 | 0 | 4 | 4 | 3.27 | .283 | 1.17 | 6.1 | 4.4 | 7.6 | 88.0 | 60 | 32 | 32 | 6 | 43 | 74 | 0 | 0 | 1 | 0 | 0 | 1 | 4 | 3.70 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 73 | 62 | 0 | 5 | 3 | 2.71 | .241 | 0.95 | 6.7 | 1.9 | 8.3 | 79.2 | 59 | 25 | 24 | 8 | 17 | 73 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.11 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 58 | 24 | 0 | 2 | 2 | 5.42 | .330 | 1.45 | 8.4 | 4.7 | 6.4 | 88.0 | 82 | 57 | 53 | 15 | 46 | 63 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 5.42 |