| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 20 | 20 | 6 | 8 | 3.49 | .295 | 1.23 | 7.9 | 3.2 | 8.0 | 139.1 | 122 | 56 | 54 | 14 | 49 | 124 | 1 | 0 | 0 | 1 | 13 | 4 | 3 | 3.67 |
| SP | DeLeon, J.DeLeon, Jose # >> | 29 | 1989 | R | 60 | 20 | 20 | 3 | 11 | 4.34 | .329 | 1.45 | 9.1 | 4.1 | 6.7 | 132.2 | 133 | 77 | 64 | 19 | 60 | 98 | 1 | 0 | 0 | 0 | 12 | 2 | 1 | 4.80 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 58 | 19 | 19 | 3 | 7 | 4.93 | .348 | 1.54 | 10.2 | 3.7 | 6.1 | 111.1 | 126 | 64 | 61 | 9 | 46 | 75 | 0 | 0 | 0 | 0 | 9 | 6 | 3 | 4.11 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 57 | 19 | 18 | 4 | 5 | 4.37 | .297 | 1.25 | 8.8 | 2.4 | 6.6 | 136.0 | 133 | 67 | 66 | 25 | 37 | 99 | 3 | 0 | 0 | 2 | 6 | 2 | 6 | 4.79 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 52 | 0 | 3 | 4 | 3.97 | .308 | 1.31 | 7.2 | 4.6 | 11.2 | 70.1 | 56 | 34 | 31 | 12 | 36 | 87 | 0 | 3 | 3 | 0 | 0 | 2 | 2 | 4.37 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 64 | 50 | 0 | 7 | 8 | 4.12 | .290 | 1.23 | 8.2 | 3.0 | 10.3 | 54.2 | 49 | 30 | 25 | 8 | 18 | 62 | 0 | 4 | 7 | 0 | 0 | 0 | 0 | 3.63 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 57 | 36 | 0 | 5 | 3 | 2.72 | .308 | 1.31 | 8.5 | 3.5 | 10.6 | 39.2 | 37 | 18 | 12 | 2 | 15 | 46 | 0 | 3 | 3 | 0 | 0 | 1 | 2 | 2.54 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 52 | 11 | 1 | 2 | 1 | 5.67 | .336 | 1.48 | 10.0 | 3.3 | 8.0 | 27.0 | 30 | 17 | 17 | 4 | 10 | 24 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.37 |