| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 11 | 10 | 5 | 3 | 3.17 | .268 | 1.06 | 6.8 | 2.7 | 6.0 | 71.0 | 54 | 27 | 25 | 10 | 21 | 47 | 3 | 1 | 0 | 0 | 7 | 3 | 0 | 4.52 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 11 | 11 | 5 | 3 | 3.39 | .279 | 1.15 | 6.8 | 3.5 | 9.1 | 66.1 | 50 | 29 | 25 | 8 | 26 | 67 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 3.77 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 10 | 10 | 3 | 4 | 5.34 | .311 | 1.34 | 9.2 | 3.0 | 8.3 | 60.2 | 61 | 40 | 36 | 12 | 20 | 55 | 1 | 0 | 0 | 1 | 4 | 1 | 4 | 4.82 |
| SP | Tanana, F.Tanana, Frank # >> | 23 | 1976 | L | 72 | 10 | 10 | 3 | 6 | 4.27 | .286 | 1.19 | 7.9 | 2.9 | 7.0 | 71.2 | 62 | 34 | 34 | 9 | 23 | 55 | 2 | 0 | 0 | 0 | 4 | 1 | 3 | 4.11 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 10 | 10 | 4 | 3 | 4.00 | .302 | 1.30 | 8.3 | 3.3 | 10.0 | 54.0 | 50 | 30 | 24 | 9 | 20 | 60 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 4.06 |
| CL | Adams, M.Adams, Mike $ >> | 31 | 2009 | R | 99 | 19 | 0 | 1 | 2 | 4.96 | .300 | 1.29 | 8.4 | 3.4 | 11.3 | 16.1 | 15 | 9 | 9 | 1 | 6 | 20 | 0 | 10 | 1 | 0 | 0 | 0 | 0 | 2.44 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 83 | 26 | 0 | 3 | 1 | 1.89 | .265 | 1.08 | 7.9 | 1.9 | 8.5 | 33.1 | 29 | 7 | 7 | 2 | 7 | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.55 |
| SU | Capps, C.Capps, Carter $ >> | 24 | 2015 | R | 83 | 13 | 0 | 0 | 0 | 2.19 | .196 | 0.73 | 3.8 | 3.0 | 12.0 | 12.1 | 5 | 4 | 3 | 1 | 4 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.42 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 22 | 0 | 0 | 1 | 4.18 | .336 | 1.52 | 7.8 | 6.3 | 9.8 | 23.2 | 20 | 11 | 11 | 3 | 16 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.61 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 79 | 14 | 0 | 2 | 1 | 6.43 | .276 | 1.14 | 7.7 | 2.6 | 10.9 | 14.0 | 12 | 10 | 10 | 4 | 4 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.14 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 74 | 9 | 0 | 0 | 1 | 6.00 | .357 | 1.67 | 12.0 | 3.0 | 8.0 | 9.0 | 12 | 6 | 6 | 3 | 3 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.56 |