| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 10 | 10 | 4 | 4 | 3.95 | .289 | 1.22 | 8.3 | 2.7 | 10.8 | 73.0 | 67 | 33 | 32 | 9 | 22 | 88 | 1 | 0 | 0 | 0 | 6 | 0 | 3 | 3.10 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 10 | 10 | 4 | 4 | 4.55 | .319 | 1.37 | 10.3 | 2.1 | 8.3 | 63.1 | 72 | 32 | 32 | 11 | 15 | 58 | 1 | 0 | 0 | 0 | 6 | 2 | 5 | 4.24 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 10 | 10 | 5 | 3 | 6.02 | .340 | 1.53 | 9.3 | 4.5 | 7.8 | 52.1 | 54 | 35 | 35 | 6 | 26 | 45 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.33 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 73 | 11 | 10 | 0 | 7 | 6.65 | .364 | 1.67 | 11.9 | 3.1 | 11.3 | 46.0 | 61 | 37 | 34 | 11 | 16 | 58 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 4.76 |
| RP | Edwards, C.Edwards, Carl $ >> | 24 | 2016 | R | 93 | 31 | 0 | 0 | 2 | 5.17 | .309 | 1.31 | 7.3 | 4.6 | 11.0 | 31.1 | 25 | 18 | 18 | 4 | 16 | 38 | 0 | 0 | 1 | 0 | 0 | 1 | 6 | 3.87 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 77 | 28 | 0 | 0 | 1 | 4.66 | .310 | 1.24 | 6.5 | 4.7 | 8.1 | 29.0 | 21 | 15 | 15 | 3 | 15 | 26 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 4.41 |
| CL | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 87 | 25 | 0 | 0 | 3 | 6.75 | .321 | 1.42 | 7.9 | 4.9 | 12.4 | 24.0 | 21 | 18 | 18 | 8 | 13 | 33 | 0 | 13 | 2 | 0 | 0 | 0 | 2 | 6.21 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 68 | 18 | 0 | 0 | 0 | 2.50 | .333 | 1.44 | 7.0 | 6.0 | 9.5 | 18.0 | 14 | 5 | 5 | 2 | 12 | 19 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.50 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 17 | 0 | 0 | 2 | 4.03 | .295 | 1.25 | 7.8 | 3.7 | 9.4 | 22.1 | 19 | 10 | 10 | 5 | 9 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.09 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 13 | 0 | 1 | 0 | 5.14 | .408 | 1.93 | 12.9 | 4.5 | 11.6 | 14.0 | 20 | 8 | 8 | 3 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.14 |