| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 90 | 32 | 32 | 4 | 14 | 6.32 | .353 | 1.60 | 10.9 | 3.5 | 9.1 | 155.1 | 188 | 110 | 109 | 38 | 61 | 156 | 0 | 0 | 0 | 0 | 11 | 5 | 7 | 5.45 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 32 | 32 | 5 | 14 | 6.01 | .334 | 1.48 | 9.4 | 3.9 | 8.3 | 149.2 | 156 | 107 | 100 | 25 | 65 | 137 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 4.73 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 31 | 30 | 14 | 9 | 5.12 | .307 | 1.31 | 9.0 | 2.8 | 5.8 | 181.0 | 182 | 106 | 103 | 30 | 56 | 117 | 3 | 0 | 0 | 0 | 15 | 2 | 3 | 4.82 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 79 | 0 | 5 | 6 | 2.54 | .254 | 1.00 | 6.5 | 2.5 | 8.8 | 85.0 | 61 | 24 | 24 | 8 | 24 | 83 | 0 | 36 | 5 | 0 | 0 | 2 | 1 | 3.19 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 88 | 79 | 0 | 5 | 5 | 3.72 | .301 | 1.26 | 7.0 | 4.4 | 8.9 | 94.1 | 73 | 40 | 39 | 6 | 46 | 93 | 0 | 7 | 3 | 0 | 0 | 3 | 0 | 3.41 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 82 | 82 | 0 | 6 | 3 | 4.39 | .300 | 1.24 | 8.0 | 3.2 | 9.3 | 106.2 | 94 | 56 | 52 | 11 | 38 | 110 | 0 | 2 | 0 | 0 | 0 | 5 | 0 | 3.49 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 65 | 0 | 8 | 2 | 3.58 | .315 | 1.34 | 8.4 | 3.7 | 8.6 | 70.1 | 65 | 28 | 28 | 9 | 29 | 67 | 0 | 2 | 2 | 0 | 0 | 3 | 2 | 4.13 |