| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 20 | 20 | 7 | 9 | 4.15 | .294 | 1.24 | 8.6 | 2.6 | 9.7 | 138.2 | 132 | 65 | 64 | 22 | 40 | 149 | 1 | 0 | 0 | 0 | 11 | 1 | 1 | 3.80 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 20 | 20 | 5 | 9 | 5.58 | .340 | 1.51 | 9.8 | 3.8 | 6.3 | 108.0 | 118 | 72 | 67 | 24 | 45 | 75 | 2 | 0 | 0 | 1 | 8 | 4 | 6 | 5.86 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 19 | 19 | 6 | 7 | 5.10 | .333 | 1.49 | 9.8 | 3.6 | 6.3 | 107.2 | 117 | 63 | 61 | 18 | 43 | 75 | 1 | 0 | 0 | 0 | 9 | 1 | 5 | 5.02 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 90 | 20 | 19 | 9 | 7 | 3.38 | .270 | 1.10 | 7.2 | 2.7 | 8.7 | 125.1 | 100 | 49 | 47 | 17 | 38 | 121 | 1 | 0 | 1 | 1 | 13 | 1 | 0 | 3.77 |
| CL | Doolittle, S.Doolittle, Sean † $ >> | 31 | 2018 | L | 98 | 47 | 0 | 2 | 4 | 5.98 | .296 | 1.24 | 8.8 | 2.5 | 10.7 | 43.2 | 42 | 31 | 29 | 9 | 12 | 51 | 0 | 24 | 3 | 0 | 0 | 1 | 2 | 4.26 |
| SU | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 45 | 0 | 2 | 5 | 3.33 | .281 | 1.15 | 7.9 | 2.6 | 9.2 | 48.2 | 42 | 18 | 18 | 6 | 14 | 49 | 0 | 0 | 3 | 0 | 0 | 1 | 3 | 3.52 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 53 | 0 | 5 | 3 | 3.25 | .265 | 1.05 | 5.8 | 3.7 | 8.4 | 61.0 | 39 | 22 | 22 | 7 | 25 | 57 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 3.95 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 40 | 0 | 2 | 1 | 4.35 | .326 | 1.40 | 6.4 | 6.4 | 10.1 | 41.1 | 29 | 21 | 20 | 8 | 29 | 46 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 5.56 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 73 | 32 | 0 | 0 | 0 | 4.94 | .321 | 1.39 | 8.7 | 3.8 | 7.3 | 31.0 | 30 | 17 | 17 | 3 | 13 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.00 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 65 | 19 | 0 | 2 | 1 | 4.58 | .309 | 1.29 | 8.7 | 2.9 | 5.2 | 59.0 | 57 | 34 | 30 | 5 | 19 | 34 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 4.07 |