| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 95 | 11 | 11 | 5 | 5 | 4.81 | .296 | 1.25 | 8.4 | 2.8 | 9.2 | 73.0 | 68 | 42 | 39 | 10 | 23 | 75 | 1 | 0 | 0 | 0 | 6 | 1 | 0 | 3.71 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 10 | 10 | 5 | 4 | 4.16 | .305 | 1.30 | 8.4 | 3.4 | 5.6 | 71.1 | 66 | 33 | 33 | 8 | 27 | 44 | 2 | 0 | 0 | 1 | 6 | 1 | 2 | 4.41 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 10 | 10 | 3 | 4 | 3.39 | .298 | 1.28 | 8.1 | 3.4 | 9.4 | 69.0 | 62 | 26 | 26 | 3 | 26 | 72 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 2.61 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 10 | 10 | 7 | 1 | 3.82 | .305 | 1.32 | 9.5 | 2.4 | 6.9 | 68.1 | 72 | 30 | 29 | 8 | 18 | 52 | 1 | 0 | 0 | 1 | 6 | 0 | 2 | 3.79 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 9 | 1 | 0 | 0 | 5.17 | .319 | 1.37 | 9.9 | 2.6 | 6.1 | 31.1 | 34 | 19 | 18 | 4 | 9 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.29 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 12 | 0 | 1 | 0 | 0.00 | .255 | 1.03 | 7.4 | 2.5 | 11.5 | 11.2 | 9 | 0 | 0 | 0 | 3 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.27 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 19 | 0 | 2 | 3 | 6.38 | .353 | 1.64 | 10.5 | 4.5 | 9.5 | 18.1 | 21 | 13 | 13 | 1 | 9 | 19 | 0 | 10 | 3 | 0 | 0 | 0 | 0 | 3.11 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 6 | 0 | 1 | 0 | 1.23 | .290 | 1.16 | 5.8 | 5.1 | 5.8 | 14.2 | 9 | 2 | 2 | 0 | 8 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 5 | 0 | 0 | 0 | 5.68 | .296 | 1.26 | 4.5 | 7.5 | 10.5 | 6.1 | 3 | 4 | 4 | 0 | 5 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.17 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 75 | 10 | 9 | 0 | 5 | 8.25 | .387 | 1.80 | 11.8 | 4.5 | 5.4 | 52.1 | 68 | 51 | 48 | 11 | 26 | 31 | 1 | 0 | 0 | 0 | 1 | 5 | 3 | 6.35 |