| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 94 | 6 | 6 | 5 | 1 | 2.50 | .267 | 1.03 | 7.4 | 2.0 | 8.8 | 50.1 | 41 | 15 | 14 | 2 | 11 | 49 | 4 | 0 | 0 | 1 | 4 | 3 | 0 | 2.40 |
| SP | Roark, T.Roark, Tanner >> | 26 | 2013 | R | 86 | 5 | 5 | 0 | 1 | 4.09 | .389 | 1.91 | 13.1 | 4.1 | 5.7 | 11.0 | 16 | 9 | 5 | 0 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.09 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 98 | 5 | 5 | 0 | 3 | 14.21 | .447 | 2.37 | 14.7 | 6.6 | 9.0 | 19.0 | 31 | 30 | 30 | 6 | 14 | 19 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 7.47 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 82 | 5 | 5 | 1 | 2 | 6.10 | .340 | 1.55 | 10.2 | 3.8 | 7.5 | 31.0 | 35 | 22 | 21 | 4 | 13 | 26 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.26 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 75 | 5 | 5 | 2 | 1 | 4.21 | .278 | 1.16 | 8.5 | 2.0 | 8.5 | 36.1 | 34 | 17 | 17 | 8 | 8 | 34 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 4.67 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 16 | 0 | 1 | 1 | 7.90 | .305 | 1.32 | 9.0 | 3.5 | 11.8 | 13.2 | 13 | 12 | 12 | 3 | 5 | 17 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 4.54 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 86 | 15 | 0 | 3 | 2 | 4.15 | .350 | 1.56 | 10.1 | 4.2 | 7.9 | 17.1 | 19 | 14 | 8 | 0 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.82 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 89 | 15 | 0 | 1 | 0 | 2.04 | .312 | 1.36 | 9.5 | 3.2 | 6.9 | 17.2 | 18 | 5 | 4 | 2 | 6 | 13 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.06 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 84 | 11 | 0 | 0 | 1 | 4.38 | .288 | 1.22 | 7.5 | 3.8 | 9.8 | 12.1 | 10 | 6 | 6 | 1 | 5 | 13 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.17 |
| RP | Hudson, D.Hudson, Daniel >> | 34 | 2021 | R | 68 | 8 | 0 | 0 | 0 | 3.48 | .279 | 1.16 | 9.9 | 0.9 | 9.0 | 10.1 | 11 | 4 | 4 | 1 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 81 | 6 | 0 | 1 | 0 | 2.08 | .350 | 1.62 | 10.1 | 5.6 | 10.1 | 8.2 | 9 | 2 | 2 | 2 | 5 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.88 |