| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 34 | 34 | 10 | 15 | 4.31 | .324 | 1.39 | 8.8 | 3.8 | 9.2 | 225.2 | 219 | 113 | 108 | 28 | 95 | 229 | 5 | 0 | 0 | 1 | 21 | 11 | 14 | 4.00 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 68 | 32 | 32 | 12 | 17 | 4.70 | .323 | 1.39 | 9.9 | 2.7 | 5.7 | 227.2 | 249 | 126 | 119 | 36 | 67 | 144 | 6 | 0 | 0 | 2 | 14 | 10 | 2 | 4.81 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 51 | 32 | 32 | 2 | 19 | 6.52 | .370 | 1.72 | 11.2 | 4.3 | 7.0 | 172.2 | 214 | 136 | 125 | 25 | 83 | 134 | 0 | 0 | 0 | 0 | 10 | 7 | 3 | 4.90 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 50 | 31 | 31 | 6 | 14 | 4.68 | .338 | 1.49 | 10.5 | 2.9 | 6.7 | 198.0 | 231 | 109 | 103 | 24 | 64 | 148 | 0 | 0 | 0 | 0 | 12 | 8 | 3 | 4.17 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 49 | 63 | 0 | 4 | 5 | 4.93 | .313 | 1.34 | 9.4 | 2.7 | 5.3 | 73.0 | 76 | 42 | 40 | 12 | 22 | 43 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 4.95 |
| RP | Remlinger, M.Remlinger, Mike >> | 36 | 2002 | L | 35 | 42 | 0 | 1 | 3 | 4.30 | .337 | 1.46 | 8.8 | 4.3 | 8.2 | 46.0 | 45 | 23 | 22 | 4 | 22 | 42 | 0 | 7 | 2 | 0 | 0 | 3 | 0 | 3.93 |
| SP | Appier, K.Appier, Kevin >> | 34 | 2001 | R | 37 | 24 | 0 | 3 | 5 | 6.69 | .386 | 1.83 | 11.5 | 5.2 | 6.3 | 40.1 | 51 | 33 | 30 | 3 | 23 | 28 | 0 | 2 | 3 | 0 | 0 | 2 | 4 | 4.45 |