| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 93 | 34 | 34 | 14 | 11 | 4.32 | .303 | 1.28 | 9.2 | 2.4 | 9.5 | 239.2 | 243 | 116 | 115 | 34 | 64 | 251 | 2 | 0 | 0 | 0 | 19 | 6 | 3 | 3.63 |
| SP | Hudson, T.Hudson, Tim # >> | 28 | 2003 | R | 73 | 33 | 33 | 10 | 12 | 3.86 | .286 | 1.17 | 7.9 | 2.6 | 6.7 | 240.0 | 210 | 105 | 103 | 37 | 70 | 179 | 6 | 0 | 0 | 3 | 18 | 8 | 6 | 4.49 |
| SP | Nolasco, R.Nolasco, Ricky # >> | 26 | 2008 | R | 56 | 32 | 32 | 10 | 14 | 4.54 | .310 | 1.31 | 9.0 | 2.8 | 6.2 | 206.1 | 207 | 107 | 104 | 30 | 64 | 142 | 4 | 0 | 0 | 1 | 15 | 7 | 2 | 4.55 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 55 | 32 | 32 | 4 | 18 | 5.98 | .339 | 1.48 | 10.2 | 3.1 | 6.5 | 182.0 | 207 | 125 | 121 | 31 | 62 | 132 | 3 | 0 | 0 | 0 | 13 | 11 | 0 | 4.97 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 85 | 0 | 5 | 4 | 3.04 | .272 | 1.10 | 7.2 | 2.7 | 6.7 | 115.1 | 92 | 41 | 39 | 6 | 35 | 85 | 0 | 6 | 6 | 0 | 0 | 2 | 1 | 3.17 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 73 | 71 | 0 | 4 | 3 | 3.19 | .289 | 1.21 | 6.9 | 4.0 | 6.9 | 90.1 | 69 | 33 | 32 | 8 | 40 | 69 | 0 | 10 | 3 | 0 | 0 | 1 | 2 | 3.99 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 53 | 60 | 0 | 8 | 5 | 3.99 | .293 | 1.21 | 7.8 | 3.1 | 7.8 | 70.0 | 61 | 34 | 31 | 9 | 24 | 61 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 4.04 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 40 | 42 | 0 | 4 | 2 | 4.09 | .313 | 1.34 | 10.2 | 1.8 | 3.9 | 44.0 | 50 | 21 | 20 | 8 | 9 | 19 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 5.18 |
| RP | Stewart, S.Stewart, Scott >> | 27 | 2002 | L | 28 | 36 | 0 | 2 | 6 | 5.13 | .307 | 1.27 | 8.0 | 3.4 | 10.1 | 47.1 | 42 | 27 | 27 | 5 | 18 | 53 | 0 | 1 | 3 | 0 | 0 | 3 | 0 | 3.47 |