| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 3 | 3 | 1 | 1 | 4.18 | .245 | 0.97 | 6.3 | 2.7 | 10.6 | 23.2 | 16 | 12 | 11 | 4 | 7 | 27 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 3.83 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 87 | 3 | 3 | 1 | 2 | 5.40 | .270 | 1.06 | 7.7 | 2.1 | 8.1 | 21.2 | 18 | 14 | 13 | 6 | 5 | 19 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 5.76 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 3 | 3 | 1 | 0 | 8.10 | .326 | 1.45 | 8.1 | 5.0 | 9.0 | 20.0 | 18 | 18 | 18 | 6 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.55 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 86 | 3 | 3 | 1 | 1 | 5.40 | .265 | 1.08 | 7.3 | 2.8 | 6.8 | 16.2 | 13 | 10 | 10 | 4 | 5 | 12 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 5.69 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 3 | 3 | 2 | 1 | 4.66 | .310 | 1.24 | 8.1 | 3.3 | 9.5 | 19.1 | 17 | 10 | 10 | 4 | 7 | 20 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 5.05 |
| CL | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 7 | 0 | 1 | 0 | 2.25 | .200 | 0.75 | 6.8 | 0.0 | 7.9 | 8.0 | 6 | 2 | 2 | 1 | 0 | 7 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 2.88 |
| SU | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 7 | 0 | 1 | 0 | 1.29 | .160 | 0.57 | 3.9 | 1.3 | 6.4 | 7.0 | 3 | 1 | 1 | 0 | 1 | 5 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 3 | 0 | 1 | 0 | 10.13 | .385 | 1.88 | 18.0 | 4.5 | 9.0 | 2.2 | 4 | 3 | 3 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.50 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 3 | 0 | 0 | 0 | 0.00 | .167 | 0.60 | 3.0 | 3.0 | 15.0 | 3.1 | 1 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.67 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 65 | 2 | 0 | 0 | 1 | 3.00 | .182 | 0.33 | 0.0 | 3.0 | 9.0 | 3.0 | 0 | 1 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.00 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 63 | 1 | 0 | 0 | 0 | 13.50 | .333 | 1.50 | 9.0 | 4.5 | 4.5 | 2.0 | 2 | 3 | 3 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 16.50 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 58 | 1 | 0 | 0 | 0 | 2.84 | .240 | 0.95 | 9.0 | 0.0 | 0.0 | 6.1 | 6 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |