| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 17 | 17 | 8 | 5 | 3.15 | .241 | 0.94 | 6.7 | 1.8 | 10.6 | 123.0 | 92 | 44 | 43 | 18 | 24 | 145 | 0 | 0 | 0 | 0 | 12 | 1 | 0 | 3.15 |
| SP | Wheeler, Z.Wheeler, Zack # >> | 35 | 2025 | R | 99 | 17 | 17 | 8 | 6 | 4.82 | .311 | 1.32 | 9.2 | 2.8 | 11.6 | 102.2 | 104 | 55 | 55 | 17 | 32 | 131 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 3.63 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 89 | 17 | 17 | 4 | 7 | 6.85 | .360 | 1.65 | 11.2 | 3.7 | 10.1 | 92.0 | 114 | 72 | 70 | 19 | 38 | 103 | 0 | 0 | 0 | 0 | 4 | 3 | 6 | 4.78 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 73 | 16 | 16 | 3 | 6 | 3.69 | .336 | 1.51 | 9.9 | 3.7 | 9.8 | 90.1 | 99 | 39 | 37 | 13 | 37 | 98 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 3.97 |
| RP | Melton, T.Melton, Troy >> | 24 | 2025 | R | 89 | 47 | 0 | 3 | 1 | 3.81 | .306 | 1.28 | 8.0 | 3.6 | 8.1 | 78.0 | 69 | 34 | 33 | 11 | 31 | 70 | 0 | 1 | 2 | 0 | 0 | 3 | 1 | 4.35 |
| RP | Strahm, M.Strahm, Matt >> | 33 | 2025 | L | 89 | 46 | 0 | 0 | 3 | 7.36 | .345 | 1.58 | 10.3 | 4.3 | 8.8 | 36.2 | 41 | 30 | 30 | 5 | 17 | 35 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.28 |
| RP | Finnegan, K.Finnegan, Kyle >> | 33 | 2025 | R | 80 | 45 | 0 | 1 | 1 | 3.66 | .329 | 1.47 | 8.7 | 4.5 | 9.6 | 32.0 | 31 | 13 | 13 | 4 | 16 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.00 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 82 | 37 | 0 | 0 | 0 | 2.13 | .315 | 1.38 | 10.4 | 2.2 | 8.6 | 25.1 | 29 | 6 | 6 | 1 | 6 | 24 | 0 | 2 | 4 | 0 | 0 | 0 | 3 | 2.32 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 76 | 22 | 0 | 1 | 0 | 1.65 | .258 | 1.04 | 7.9 | 1.7 | 7.3 | 16.1 | 14 | 3 | 3 | 1 | 3 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.75 |