| SP | Martinez, P.Martinez, Pedro # >> | 26 | 1997 | R | 81 | 36 | 36 | 13 | 13 | 4.93 | .326 | 1.42 | 9.5 | 3.3 | 9.3 | 215.1 | 228 | 126 | 118 | 37 | 78 | 222 | 6 | 0 | 0 | 2 | 17 | 6 | 4 | 4.34 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 90 | 32 | 32 | 11 | 13 | 3.65 | .310 | 1.32 | 8.0 | 3.9 | 9.3 | 200.0 | 178 | 83 | 81 | 15 | 86 | 207 | 0 | 0 | 0 | 0 | 20 | 5 | 8 | 3.27 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 65 | 34 | 33 | 12 | 11 | 3.75 | .290 | 1.21 | 7.8 | 3.1 | 5.8 | 168.0 | 146 | 71 | 70 | 23 | 58 | 108 | 1 | 1 | 0 | 0 | 17 | 2 | 5 | 4.57 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 50 | 34 | 33 | 10 | 9 | 5.15 | .318 | 1.38 | 8.9 | 3.6 | 9.1 | 138.0 | 136 | 84 | 79 | 24 | 55 | 140 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.47 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 85 | 94 | 0 | 10 | 2 | 3.27 | .300 | 1.27 | 7.7 | 3.7 | 4.3 | 159.2 | 136 | 69 | 58 | 13 | 66 | 76 | 0 | 0 | 5 | 0 | 0 | 3 | 2 | 4.41 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 97 | 72 | 0 | 4 | 5 | 2.24 | .265 | 1.06 | 7.3 | 2.3 | 9.2 | 84.1 | 68 | 22 | 21 | 6 | 21 | 86 | 0 | 34 | 5 | 0 | 0 | 2 | 1 | 2.70 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 81 | 83 | 0 | 5 | 4 | 2.77 | .281 | 1.15 | 6.3 | 4.1 | 8.0 | 110.2 | 77 | 35 | 34 | 13 | 50 | 98 | 0 | 2 | 3 | 0 | 0 | 3 | 3 | 4.20 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 78 | 73 | 0 | 6 | 1 | 3.04 | .265 | 1.03 | 6.9 | 2.4 | 8.2 | 100.2 | 77 | 36 | 34 | 4 | 27 | 91 | 0 | 5 | 2 | 0 | 0 | 5 | 0 | 2.66 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 61 | 64 | 0 | 4 | 1 | 4.08 | .262 | 1.04 | 8.0 | 1.3 | 9.1 | 75.0 | 67 | 37 | 34 | 9 | 11 | 76 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.05 |
| RP | Hudson, D.Hudson, Daniel >> | 34 | 2021 | R | 50 | 49 | 0 | 4 | 1 | 4.50 | .322 | 1.41 | 9.5 | 3.2 | 9.0 | 54.0 | 57 | 29 | 27 | 7 | 19 | 54 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.80 |
| RP | Valdez, S.Valdez, Sergio >> | 28 | 1992 | R | 38 | 47 | 0 | 4 | 2 | 3.84 | .310 | 1.33 | 6.5 | 5.6 | 5.4 | 58.2 | 42 | 28 | 25 | 2 | 36 | 35 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 4.16 |
| SP | Youmans, F.Youmans, Floyd # >> | 22 | 1986 | R | 52 | 32 | 30 | 8 | 10 | 4.73 | .332 | 1.45 | 8.0 | 5.1 | 6.0 | 135.0 | 120 | 79 | 71 | 19 | 76 | 90 | 0 | 1 | 0 | 0 | 9 | 5 | 6 | 5.30 |