| SP | Bender, C.Bender, Chief >> | 24 | 1908 | R | 63 | 38 | 38 | 12 | 11 | 4.58 | .321 | 1.40 | 10.2 | 2.4 | 4.9 | 228.0 | 259 | 125 | 116 | 27 | 60 | 123 | 1 | 0 | 0 | 0 | 18 | 5 | 2 | 4.32 |
| SP | Samardzija, J.Samardzija, Jeff >> | 29 | 2014 | R | 75 | 36 | 36 | 14 | 13 | 3.72 | .296 | 1.25 | 9.4 | 1.9 | 5.9 | 217.2 | 226 | 92 | 90 | 20 | 45 | 143 | 0 | 0 | 0 | 0 | 23 | 4 | 5 | 3.56 |
| SP | Waddell, R.Waddell, Rube >> | 31 | 1907 | L | 60 | 34 | 34 | 11 | 10 | 4.73 | .332 | 1.48 | 9.7 | 3.7 | 6.3 | 173.1 | 186 | 92 | 91 | 21 | 71 | 122 | 0 | 0 | 0 | 0 | 15 | 1 | 2 | 4.42 |
| SP | Hunter, C.Hunter, Catfish >> | 25 | 1971 | R | 50 | 34 | 34 | 8 | 13 | 5.72 | .348 | 1.59 | 10.6 | 3.7 | 5.3 | 170.0 | 201 | 112 | 108 | 22 | 69 | 100 | 1 | 0 | 0 | 0 | 14 | 2 | 3 | 4.76 |
| RP | Doolittle, S.Doolittle, Sean >> | 27 | 2014 | L | 88 | 85 | 0 | 7 | 1 | 3.45 | .264 | 1.05 | 7.9 | 1.6 | 8.8 | 122.2 | 107 | 48 | 47 | 14 | 22 | 119 | 0 | 7 | 4 | 0 | 0 | 3 | 0 | 3.16 |
| RP | Miller, M.Miller, Mason >> | 25 | 2024 | R | 81 | 77 | 0 | 8 | 3 | 3.64 | .274 | 1.11 | 6.0 | 4.0 | 10.1 | 101.1 | 67 | 44 | 41 | 9 | 45 | 113 | 0 | 7 | 5 | 0 | 0 | 3 | 2 | 3.35 |
| RP | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 77 | 69 | 0 | 10 | 6 | 3.06 | .294 | 1.24 | 8.5 | 2.7 | 8.7 | 82.1 | 77 | 30 | 28 | 5 | 25 | 79 | 0 | 8 | 4 | 0 | 0 | 1 | 0 | 2.82 |
| RP | Abad, F.Abad, Fernando >> | 28 | 2014 | L | 71 | 44 | 0 | 4 | 2 | 2.68 | .257 | 1.04 | 6.2 | 3.2 | 6.6 | 57.0 | 39 | 17 | 17 | 3 | 20 | 42 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.26 |
| RP | Breslow, C.Breslow, Craig >> | 29 | 2009 | L | 49 | 31 | 0 | 2 | 2 | 5.83 | .343 | 1.57 | 8.1 | 6.2 | 6.8 | 29.1 | 26 | 21 | 19 | 6 | 20 | 22 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 6.24 |
| RP | Soria, J.Soria, Joakim >> | 35 | 2019 | R | 48 | 27 | 0 | 3 | 0 | 2.76 | .279 | 1.16 | 7.4 | 3.1 | 8.7 | 29.1 | 24 | 9 | 9 | 4 | 10 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.90 |
| SP | Henley, W.Henley, Weldon >> | 25 | 1905 | R | 37 | 26 | 0 | 10 | 1 | 3.76 | .325 | 1.42 | 8.2 | 4.6 | 5.4 | 141.1 | 129 | 62 | 59 | 8 | 72 | 85 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 4.13 |
| RP | Kittredge, A.Kittredge, Andrew # >> | 35 | 2025 | R | 55 | 38 | 0 | 0 | 2 | 5.59 | .314 | 1.37 | 9.4 | 3.1 | 8.6 | 46.2 | 48 | 30 | 29 | 6 | 16 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.83 |